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    Glossary Forkhead box P3

    protein essential for regulatory T cell function and immune balance

    Forkhead box P3 (Foxp3) is a protein crucial for the normal function of regulatory T cells (Tregs), which help maintain immune system balance and prevent autoimmune diseases. Mutations in the Foxp3 gene can lead to severe autoimmune conditions, such as IPEX syndrome (Immune dysregulation, Polyendocrinopathy, Enteropathy, X-linked syndrome).

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    1. Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders Frontiers in Immunology · 2020 · 20 citations
    2. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
    3. Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates General and Comparative Endocrinology · 2020 · 21 citations
    4. Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels Nature Communications · 2019 · 40 citations
    5. Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations Journal of Clinical Immunology · 2021 · 30 citations
    6. A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice 2008 · 60 citations
    7. Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration Frontiers in Immunology · 2018 · 188 citations
    8. An Assessment on Impact of COVID-19 Infection in a Gender Specific Manner Stem Cell Reviews and Reports · 2020 · 59 citations
    9. An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities Frontiers in Cell and Developmental Biology · 2020 · 23 citations
    10. A symphony of signals: the intricate role of lncRNAs in dermatological disorders Clinical and Experimental Medicine · 2025 · 1 citations
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