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    Glossary Forkhead box P3

    protein essential for regulatory T cell function and immune balance

    Forkhead box P3 (Foxp3) is a protein crucial for the normal function of regulatory T cells (Tregs), which help maintain immune system balance and prevent autoimmune diseases. Mutations in the Foxp3 gene can lead to severe autoimmune conditions, such as IPEX syndrome (Immune dysregulation, Polyendocrinopathy, Enteropathy, X-linked syndrome).

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    1. Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders Frontiers in Immunology · 2020 · 20 citations
    2. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
    3. Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates General and Comparative Endocrinology · 2020 · 21 citations
    4. Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels Nature Communications · 2019 · 40 citations
    5. Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies Frontiers in Immunology · 2025 · 4 citations
    6. Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations Journal of Clinical Immunology · 2021 · 30 citations
    7. Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery Pharmacology & Therapeutics · 2016 · 26 citations
    8. Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes Frontiers in Cell and Developmental Biology · 2020 · 5 citations
    9. Small molecules and small molecule drugs in regenerative medicine Drug Discovery Today · 2013 · 51 citations
    10. A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice 2008 · 60 citations
    11. Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration Frontiers in Immunology · 2018 · 188 citations
    12. An Assessment on Impact of COVID-19 Infection in a Gender Specific Manner Stem Cell Reviews and Reports · 2020 · 59 citations
    13. An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities Frontiers in Cell and Developmental Biology · 2020 · 23 citations
    14. Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study Stem Cells International · 2020 · 14 citations
    15. A symphony of signals: the intricate role of lncRNAs in dermatological disorders Clinical and Experimental Medicine · 2025 · 1 citations
    16. HuR ablation destabilizes Foxp3 mRNA and impairs regulatory T cell function, contributing to an autoimmune phenotype Frontiers in Immunology · 2025 · 1 citations
    17. Hidradenitis Suppurativa/Acne Inversa/Dissecting Terminal Hair Folliculitis Springer eBooks · 2019 · 1 citations
    18. The role of protein lactylation in skin diseases: from molecular mechanisms to potential therapeutics Frontiers in Immunology · 2026
    19. Precision therapeutics in non-scarring alopecia: a systemic genomic and pathway-based framework for targeted interventions ADMET & DMPK · 2025
    20. Actinic Keratosis: Risk Factors, Clinical, Diagnosis and Therapeutics Aspects. Part I Dermatovenerologiâ, kosmetologiâ · 2024
    21. Alopecia and the Microbiome: A Future Therapeutic Target? Actas Dermo-Sifiliográficas · 2021
    22. Immunopathogenesis of Primary Cicatricial Alopecia Research Portal (King's College London) · 2013
    23. Das weiße Hautfettgewebe initiiert die IL-33-abhängige Expression von Interleukin 4/13 in myeloischen Zellen während einer Entzündung Qucosa (Saxon State and University Library Dresden) · 2024
    24. Transforming growth factor-β in stem cells and tissue homeostasis Bone Research · 2018 · 245 citations
    25. Extraskeletal actions of vitamin D Annals of the New York Academy of Sciences · 2016 · 119 citations
    26. Insulin Resistance and Skin Diseases The Scientific World Journal · 2015 · 71 citations
    27. Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter (PM10) on Human Dermal Fibroblasts International Journal of Molecular Sciences · 2018 · 68 citations
    28. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update Journal of Dermatological Science · 2012 · 52 citations
    29. Regulation of masculinization: androgen signalling for external genitalia development Nature Reviews Urology · 2018 · 45 citations
    30. Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear Neuroscience Bulletin · 2023 · 26 citations