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    Glossary Forkhead box P3

    protein essential for regulatory T cell function and immune balance

    Forkhead box P3 (Foxp3) is a protein crucial for the normal function of regulatory T cells (Tregs), which help maintain immune system balance and prevent autoimmune diseases. Mutations in the Foxp3 gene can lead to severe autoimmune conditions, such as IPEX syndrome (Immune dysregulation, Polyendocrinopathy, Enteropathy, X-linked syndrome).

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    1. Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders Frontiers in Immunology · 2020 · 20 citations
    2. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
    3. Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates General and Comparative Endocrinology · 2020 · 21 citations
    4. Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels Nature Communications · 2019 · 40 citations
    5. Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations Journal of Clinical Immunology · 2021 · 30 citations
    6. A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice 2008 · 60 citations
    7. Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration Frontiers in Immunology · 2018 · 188 citations
    8. An Assessment on Impact of COVID-19 Infection in a Gender Specific Manner Stem Cell Reviews and Reports · 2020 · 59 citations
    9. An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities Frontiers in Cell and Developmental Biology · 2020 · 23 citations
    10. A symphony of signals: the intricate role of lncRNAs in dermatological disorders Clinical and Experimental Medicine · 2025 · 1 citations
    11. HuR ablation destabilizes Foxp3 mRNA and impairs regulatory T cell function, contributing to an autoimmune phenotype Frontiers in Immunology · 2025 · 1 citations
    12. Hidradenitis Suppurativa/Acne Inversa/Dissecting Terminal Hair Folliculitis Springer eBooks · 2019 · 1 citations
    13. The role of protein lactylation in skin diseases: from molecular mechanisms to potential therapeutics Frontiers in Immunology · 2026
    14. Precision therapeutics in non-scarring alopecia: a systemic genomic and pathway-based framework for targeted interventions ADMET & DMPK · 2025
    15. Actinic Keratosis: Risk Factors, Clinical, Diagnosis and Therapeutics Aspects. Part I Dermatovenerologiâ, kosmetologiâ · 2024
    16. Immunopathogenesis of Primary Cicatricial Alopecia Research Portal (King's College London) · 2013
    17. Das weiße Hautfettgewebe initiiert die IL-33-abhängige Expression von Interleukin 4/13 in myeloischen Zellen während einer Entzündung Qucosa (Saxon State and University Library Dresden) · 2024
    18. Extraskeletal actions of vitamin D Annals of the New York Academy of Sciences · 2016 · 119 citations
    19. Regulation of masculinization: androgen signalling for external genitalia development Nature Reviews Urology · 2018 · 45 citations
    20. Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear Neuroscience Bulletin · 2023 · 26 citations
    21. Current Perspectives on the Physiological Activities of Fermented Soybean-Derived Cheonggukjang International Journal of Molecular Sciences · 2021 · 26 citations
    22. A preliminary study of differentially expressed genes in expanded skin and normal skin: implications for adult skin regeneration Archives of Dermatological Research · 2011 · 16 citations
    23. The Critical Roles of Serum/Glucocorticoid-Regulated Kinase 3 (SGK3) in the Hair Follicle Morphogenesis and Homeostasis American Journal of Pathology · 2006 · 9 citations
    24. Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review International Journal of Medical Sciences · 2025 · 4 citations
    25. Adipose-Derived Stem/Stromal Cells Springer eBooks · 2016 · 2 citations
    26. γδ17 T cell-stromal networks modulate matrix composition and vascularity in foreign body response 2026 · 1 citations
    27. Epithelial–mesenchymal transition in cutaneous fibrosis disease: from mechanisms to therapy Frontiers in Immunology · 2026
    28. The modern scientific interpretation of ancient wisdom: a review of the phytochemistry and pharmacology of Erzhi Pill and its constituent botanical drugs Frontiers in Pharmacology · 2026
    29. Effects of Selenium and Other Micronutrient Intake on Human Health 2025
    30. Combined Physicochemical and Transcriptomic Analyses Reveal the Effect of Black Wolfberry Ferment on Alopecia Journal of Food and Nutrition Research · 2025