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    Glossary Forkhead Box N1

    gene crucial for thymus development and hair follicle regulation

    Forkhead Box N1 (Foxn1) is a gene that plays a crucial role in the development and function of the thymus, an organ important for the immune system, and in the regulation of skin and hair follicle development. Mutations in the Foxn1 gene can lead to conditions such as nude mice, which lack hair and have an underdeveloped thymus, highlighting its importance in both immune function and hair growth.

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    1. Patients with Compound Heterozygous Mutations in Forkhead Box N1 have a Severe Immunodeficiency while Maintaining Normal Skin and Hair Development 2017
    2. Compound Heterozygous Mutations in <i>Forkhead Box N1</i> (<i>FOXN1</i>) Lead to a Severe Immunodeficiency but Normal Hair and Nail Development in Patients 2018
    3. FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program Frontiers in Immunology · 2013 · 69 citations
    4. Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses Nature Genetics · 2015 · 73 citations
    5. SNP variation in male pattern hair loss in Russians with different dihydrotestosterone levels Meta Gene · 2018 · 3 citations
    6. Taking advantage from phenotype variability in a local animal genetic resource: identification of genomic regions associated with the hairless phenotype in Casertana pigs Animal Genetics · 2018 · 16 citations
    7. Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations Journal of Clinical Immunology · 2021 · 30 citations
    8. Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats PLoS ONE · 2016 · 127 citations
    9. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update Journal of Dermatological Science · 2012 · 52 citations
    10. To grow or not to grow: Hair morphogenesis and human genetic hair disorders Seminars in Cell & Developmental Biology · 2013 · 43 citations
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