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    Glossary Forkhead Box N1

    gene crucial for thymus development and hair follicle regulation

    Forkhead Box N1 (Foxn1) is a gene that plays a crucial role in the development and function of the thymus, an organ important for the immune system, and in the regulation of skin and hair follicle development. Mutations in the Foxn1 gene can lead to conditions such as nude mice, which lack hair and have an underdeveloped thymus, highlighting its importance in both immune function and hair growth.

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    1. Patients with Compound Heterozygous Mutations in Forkhead Box N1 have a Severe Immunodeficiency while Maintaining Normal Skin and Hair Development 2017
    2. Compound Heterozygous Mutations in <i>Forkhead Box N1</i> (<i>FOXN1</i>) Lead to a Severe Immunodeficiency but Normal Hair and Nail Development in Patients 2018
    3. FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program Frontiers in Immunology · 2013 · 69 citations
    4. Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses Nature Genetics · 2015 · 73 citations
    5. SNP variation in male pattern hair loss in Russians with different dihydrotestosterone levels Meta Gene · 2018 · 3 citations
    6. Taking advantage from phenotype variability in a local animal genetic resource: identification of genomic regions associated with the hairless phenotype in Casertana pigs Animal Genetics · 2018 · 16 citations
    7. Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations Journal of Clinical Immunology · 2021 · 30 citations
    8. Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats PLoS ONE · 2016 · 127 citations
    9. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update Journal of Dermatological Science · 2012 · 52 citations
    10. To grow or not to grow: Hair morphogenesis and human genetic hair disorders Seminars in Cell & Developmental Biology · 2013 · 43 citations
    11. Hair in health and disease: an introduction Wageningen Academic Publishers eBooks · 2012 · 3 citations
    12. Embryologic layers in dermatology: Developmental checkpoint disorders, diagnostic insight, and regenerative futures Italian Journal of Anatomy and Embryology · 2025
    13. Perspectives of Alopecia behind the Regulation of Foxn1 Gene Exposes the Human Nude Phenotype InTech eBooks · 2018
    14. Dissecting the boundary of quiescence and activation of murine melanocyte stem cells in the hair follicle niche npj Regenerative Medicine · 2026
    15. A preliminary study of differentially expressed genes in expanded skin and normal skin: implications for adult skin regeneration Archives of Dermatological Research · 2011 · 16 citations
    16. A novel hairless highly immunodeficient mice model optimized for in vivo imaging Laboratory Animal Research · 2026
    17. Das weiße Hautfettgewebe initiiert die IL-33-abhängige Expression von Interleukin 4/13 in myeloischen Zellen während einer Entzündung Qucosa (Saxon State and University Library Dresden) · 2024
    18. Signaling pathways and targeted therapeutic strategies for polycystic ovary syndrome Frontiers in endocrinology · 2023
    19. Avaliação do impacto da redução significativa de peso pela dieta cetogênica de muito baixa caloria nos parâmetros metabólicos, inflamatórios, hormonais e seminais de homens obesos 2023
    20. 毛乳頭細胞と毛包上皮細胞間の細胞内・細胞外情報伝達 Institutional Repositories DataBase (IRDB) · 2022
    21. Encapsulación en ciclodextrinas de compuestos con actividad frente a la alopecia androgénica masculina. RIUCAM · 2021
    22. Risk factors for prostate cancer: a case-control study investigating selected key exposures and their interactions with predisposition genes Jurnal Natural (Faculty of Mathematics and Natural Science, Syiah Kuala University) · 2010
    23. Novel Systematics of Nomenclature and Classification of Female Functional Androgenization (Including Polycystic Ovary Syndrome and Non-Classic Congenital Adrenal Hyperplasia) Journal für Kardiologie (Krause & Pachernegg GmbH) · 2010 · 8 citations
    24. Genomic prediction and genome-wide association studies of morphological traits and distraction index in Korean Sapsaree dogs PLoS ONE · 2024 · 2 citations
    25. Epstein-Barr virus associated with high-grade B-cell lymphoma in nude severe combined immunodeficiency BMJ case reports · 2019 · 3 citations
    26. Tissue expansion techniques in reconstructive surgery: a 10-year bibliometric analysis Annals of Translational Medicine · 2023 · 2 citations
    27. Dermal white adipose tissue: Development and impact on hair follicles, skin defense, and fibrosis The FASEB Journal · 2024 · 3 citations
    28. Dermal white adipose tissue development and metabolism: The role of transcription factor Foxn1 ˜The œFASEB journal · 2023
    29. Role of <i>foxn1</i> in <i>Xenopus laevis</i> thymopoiesis. 2022
    30. Foxn1 in Skin Development, Homeostasis and Wound Healing International Journal of Molecular Sciences · 2018 · 21 citations