CRISPR/Cas9: A Promising Approach for Alopecia
January 2024
in “
Biomedical journal of scientific & technical research
”
TLDR CRISPR/Cas9 gene-editing may effectively treat hair loss but requires more research for safe use.
The research paper "CRISPR/Cas9: A Promising Approach for Alopecia" discusses the potential of the CRISPR/Cas9 gene-editing technology in treating alopecia, a condition characterized by abnormal hair loss. Traditional treatments like finasteride and minoxidil often have limited efficacy and side effects. CRISPR/Cas9, however, offers a novel approach to tackle alopecia at its genetic roots. The technology has shown efficacy in stimulating hair growth in several experimental models by manipulating key genes at different phases of the hair cycle and influencing molecular pathways related to hair growth. Despite its potential, challenges in clinical implementation, such as the need for precise genetic editing, effective delivery systems, and minimization of adverse immune responses, need to be addressed. Further research on the long-term effects of CRISPR/Cas9 and clinical trials are necessary to ensure its safe application in humans.