Developing Stratified Epithelia: Lessons from the Epidermis and Thymus

    August 2014 in “ Wiley interdisciplinary reviews. Developmental biology ”
    Natalie Roberts, Valerie Horsley
    Studysummary This review highlights similarities in the development of thymus and skin epidermis, reporting no new results; the authors emphasize shared molecular mechanisms despite different embryonic origins.
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    Research cited in this study 12

    1. Early Inductive Events in Ectodermal Appendage Morphogenesis Seminars in cell & developmental biology · 2014
    2. Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair Nature · 2013
    3. FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program Frontiers in Immunology · 2013
    4. Eph/Ephrin Signaling in Epidermal Differentiation and Disease Seminars in Cell & Developmental Biology · 2011
    5. Microenvironmental Reprogramming of Thymic Epithelial Cells to Skin Multipotent Stem Cells Nature · 2010
    6. Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle Stem Cells · 2010
    7. KGF And EGF Signaling Block Hair Follicle Induction And Promote Interfollicular Epidermal Fate In Developing Mouse Skin Development · 2009
    8. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    9. Adenomatous Polyposis Coli (APC) Is Required for Normal Development of Skin and Thymus PLoS Genetics · 2006
    10. Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells Genes & development · 2005
    11. Inhibition of BMP Signaling Affects Growth and Differentiation in the Anagen Hair Follicle The EMBO Journal · 2000
    12. Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages During Skin Development The Journal of Cell Biology · 1998

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