Dermal White Adipose Tissue Development and Metabolism: The Role of Transcription Factor Foxn1

September 2023 in “ The FASEB journal ”

Katarzyna Walendzik, Marta Kopcewicz, Joanna Bukowska, Paulina Opyd, Sylwia Machcińska, Barbara Gawrońska‐Kozak

Foxn1 dermal white adipose tissue adipogenesis lipid metabolism wound healing dermal fibroblasts lipogenesis lipolysis skin homeostasis dWAT

Studysummary This study found that the protein Foxn1 is crucial for the development and fat-storing capacity of dermal white adipose tissue in mice, influencing both lipid metabolism and adipogenesis in the skin through Bmp2 and Igf2 signaling pathways.

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