TLDR Skin fat cells help with skin balance, hair growth, and healing wounds.
The 2014 document discusses the characteristics and significance of adipose tissue associated with the skin, emphasizing the layer of adipocytes beneath the reticular dermis. It notes that these intradermal adipocytes and dermal fibroblasts likely originate from a common precursor and develop independently from subcutaneous adipose tissue. The adipocytes play a crucial role in epidermal homeostasis, hair follicle regeneration, and wound healing. The authors propose using "intradermal adipocytes" and "dermal white adipose tissue (DWAT)" as terms to better define this distinct adipose compartment within the dermis, aiming to improve the understanding of its unique functions in skin and adipocyte biology.
1235 citations
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December 2013 in “Nature” Two fibroblast types shape skin structure and repair differently.
238 citations
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March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
499 citations
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September 2011 in “Cell” Fat-related cells are important for initiating hair growth.
1 citations
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November 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.
115 citations
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December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
21 citations
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March 2018 in “Experimental Dermatology” The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
49 citations
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March 2019 in “Journal of Investigative Dermatology” Skin fat plays a key role in immune defense and healing beyond just storing energy.
