65 citations
,
January 2018 in “Nature Reviews Endocrinology”
This review discusses the unique features of dermal white adipose tissue, its interaction with hair follicles, and its role in skin physiology, reporting no new experimental findings.
This study found that feeding mice a high-fat diet with fish oil leads to hair loss through a mechanism involving omega-3 fatty acids and TNF-α signaling, with epidermal fatty acid binding protein playing a key role.
93 citations
,
April 2003 in “Proceedings of the National Academy of Sciences of the United States of America”
This study identified an unexpected critical role for the FATP4 protein in skin and hair development in mice, linking it to a potential candidate gene for restrictive dermopathy in humans.
11 citations
,
July 2022 in “International Journal of Molecular Sciences”
This study found that treating reconstructed human epidermis with beta-lipohydroxy salicylic acid increased tight junction remnants in the stratum corneum, potentially affecting skin cohesion and desquamation.
1 citations
,
January 2012 in “Human health handbooks”
This review discusses the essential role of linoleic acid in preventing deficiency symptoms and enhancing skin function, but notes that scientific knowledge on its potential therapeutic use for skin diseases remains limited.
Dutasteride and finasteride can cause changes in physical appearance, like more feminine features and increased water retention. Users report side effects such as reduced libido, weight gain, and improved skin clarity, while some notice no significant changes.
A 19-year-old is experiencing early hair loss, possibly due to oily skin, stress, poor diet, and lack of sleep. They have tried ketoconazole shampoo without success and plan to visit a dermatologist for further advice.
Bimatoprost and latanoprost are being considered for scalp hair growth, with concerns about side effects like skin darkening and fat loss. A user warns about potential chemical burns from latanoprost.
The user experienced positive hair growth with finasteride but developed gut issues, dry skin, thinning eyebrows, fatigue, low libido, and erection difficulties after stopping it. They are seeking advice on whether to resume finasteride or stay off it to recover.
Hair loss is linked to excess epicardial fat, which may affect blood flow to hair follicles. Treatments mentioned include minoxidil, finasteride, and dutasteride.
Is scalp micropigmentation suitable for people with sensitive skin?Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.
Can melatonin cause side effects on the skin or hair?No study links melatonin to hair loss; reports are anecdotal. Some users report scalp dryness or irritation from topical products, and a safety review lists mainly mild side effects such as sleepiness and headache.
Can follistatin be applied to the skin, and does any form of it treat hair loss?No study shows that follistatin applied to the skin works, and no form of follistatin is an approved or proven hair-loss treatment. Follistatin injections, "research peptides" and gene therapies sold outside regulated trials are unapproved and of unknown safety.