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    GlossarySkin Lipids

    natural fats in the skin's outermost layer

    Skin lipids are natural fats found in the outermost layer of the skin, known as the stratum corneum. They play a crucial role in maintaining the skin's barrier function, keeping it hydrated, and protecting it from environmental damage. These lipids include ceramides, cholesterol, and fatty acids, which work together to prevent water loss and shield the skin from harmful substances.

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      learn Ketoconazole

      antifungal with some anti-androgenic benefits, often used as a shampoo

      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Peppermint

      herb and oil thought to stimulate skin and hair

      learn Stemoxydine

      chemical from L'Oreal that encourages hair to enter growth phase

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      community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

      in Research/Science  131 upvotes 1 week ago
      Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  6 upvotes 2 years ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  53 upvotes 2 days ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community Is 2-deoxy-D-ribose (2dDR) good for human hair?

      in Research/Science  9 upvotes 6 months ago
      Topical 2-deoxy-D-ribose (2dDR) regrows hair in mice almost as well as 2% Minoxidil. However, 2dDR may contribute to oxidative stress and hair loss due to the formation of advanced glycation end products (AGEs).