LC/MS Analysis of Stratum Corneum Lipids: Ceramide Profiling and Discovery

    March 2011 in “ Journal of Lipid Research
    Jeroen van Smeden, Louise Hoppel, Rob van der Heijden, Thomas Hankemeier, Rob J. Vreeken, Joke A. Bouwstra
    TLDR A new, quick method was developed to analyze skin lipids, discovering a new ceramide subclass.
    The study from June 2011 developed a novel LC/MS method for analyzing ceramides in the stratum corneum, identifying all 11 known ceramide subclasses and discovering a new subclass, CER [EOdS]. This method was quick, robust, and required minimal sample preparation, showing slight differences in ceramide profiles among various human skin samples. The method offered advantages over previous techniques, including reduced analysis time and higher sensitivity, making it suitable for detailed ceramide profiling in skin research. The study concluded that this new method is beneficial for future ceramide analysis.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 21 results

    Similar Research

    5 / 1000+ results