Sphingolipids of the Murine Hair

    Mikiko Abe, Eriko Oshima, Shota Sakai, Yoshio Hirabayashi, Tetsuya Tsuchida, Sumiko Hamanaka
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    TLDR Murine hair has specific types of ceramides and glucosylceramides but lacks acylceramides.
    The study analyzed the sphingolipids in murine hair, focusing on ceramides, glucosylceramides, and sphingomyelins. It found that murine hair contains ceramides with dihydrosphingosine and glucosylceramides with both saturated and unsaturated fatty acids, but lacks acylceramides. Sphingomyelin was mostly absent in the hair shaft but present in the hair follicle, with its fatty acids primarily being saturated. The findings suggested that ceramides, glucosylceramides, and sphingomyelins in hair have different metabolic processes and functions.
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