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    Glossary Sebum

    oily substance produced by sebaceous glands in skin

    Sebum is an oily substance produced by sebaceous glands in the skin. It helps to lubricate and waterproof the skin and hair, providing a protective barrier against external elements. Sebum is composed of triglycerides, wax esters, squalene, and free fatty acids, and its overproduction can contribute to conditions like acne.

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    Community 10 of 375

    1. How to deal with overproduction of sebum? Reddit · 17 Aug 2026
    2. Do dut and fin reduce sebum causing frizzy hair? Reddit · 20 Apr 2026
    3. Sebum on scalp has reduced, what gives ? Reddit · 9 Feb 2026
    4. Can absorption be intervened by oil, sebum etc? Reddit · 27 Aug 2024
    5. For people with overly oily hair, does topical finasteride/dutasteride/antiandrogens (like RU or Pyrilutamide) reduce sebum overproduction? Reddit · 26 Apr 2023
    6. Can less frequent hair washing kickstart MPB due to sebum buildup? Reddit · 4 Mar 2021
    7. Sebum production even on dutasteride, and its relation to MPB. Reddit · 14 Dec 2025
    8. Does Pyrilutamide lowers sebum production? Reddit · 22 Nov 2025
    9. Can the ingredients in a sebum-regulating shampoo induce hair diameter reduction? Reddit · 13 Oct 2024
    10. Serum DHT CAN'T cause hair loss. Sebum DHT is a better measurement. Reddit · 24 Sept 2024
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    Research 10 of 1000+

    1. Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating β-Defensin-2 Expression Journal of Investigative Dermatology · 2009 · 195 citations
    2. Terbinafine levels in serum, stratum corneum, dermis-epidermis (without stratum corneum), hair, sebum and eccrine sweat. Acta dermato-venereologica · 1991 · 121 citations
    3. Ceramide synthase 4 deficiency in mice causes lipid alterations in sebum and results in alopecia Biochemical Journal · 2014 · 67 citations
    4. The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia Journal of The American Academy of Dermatology · 1999 · 65 citations
    5. Normal Fur Development and Sebum Production Depends on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands 2011 · 40 citations
    6. Inhibition of Rat 5<i>α</i>-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of<i>Quercus acutissima</i>Cortex Evidence-based Complementary and Alternative Medicine · 2015 · 37 citations
    7. MK-386, an Inhibitor of 5α-Reductase Type 1, Reduces Dihydrotestosterone Concentrations in Serum and Sebum without Affecting Dihydrotestosterone Concentrations in Semen<sup>1</sup> The Journal of Clinical Endocrinology & Metabolism · 1997 · 37 citations
    8. Investigation of drug partition property in artificial sebum International Journal of Pharmaceutics · 2007 · 33 citations
    9. Female pattern hair loss, sebum excretion and the end-organ response to androgens British Journal of Dermatology · 2005 · 31 citations
    10. Diffusion properties of model compounds in artificial sebum International journal of pharmaceutics · 2007 · 29 citations
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