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    GlossarySebaceous Gland Activity

    production of sebum by skin glands

    Sebaceous gland activity refers to the function of sebaceous glands in the skin, which produce and secrete an oily substance called sebum. Sebum helps to lubricate and protect the skin and hair, but excessive activity can lead to oily skin and conditions like acne, while insufficient activity can result in dry skin.

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      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  63 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community How many of you guys have taken accutane?

      in Chat  8 upvotes 1 week ago
      Accutane may accelerate hair loss in genetically predisposed individuals by affecting enzymes related to DHT metabolism. Some users report hair loss after taking Accutane, while others use treatments like finasteride and minoxidil to manage hair loss.

      community Finasteride gives me seb derm. Thoughts on zinc or other options?

      in Chat  16 upvotes 3 years ago
      A user with diffuse hair loss after taking accutane, which might have triggered genetic predisposition to AGA; their experience taking finasteride and experiencing side effects of increased oil production, increased sex drive, worsening hair texture; they are considering zinc supplementation with finasteride or other treatments such as alfatradiol or spironolactone.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  408 upvotes 1 month ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.