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research Risk factors for sebaceous gland diseases and their relationship to gastrointestinal dysfunction in Han adolescents

66 citations , September 2008 in “The Journal of Dermatology”

This study found that gastrointestinal dysfunction is a significant risk factor for sebaceous gland diseases in adolescents, with correlations observed between these conditions and various GI symptoms.

research Sebaceous gland loss and inflammation in scarring alopecia: A potential role in pathogenesis

37 citations , June 2011 in “Journal of The American Academy of Dermatology”

This study demonstrates that sebaceous gland loss is a common early feature in primary scarring alopecia and suggests that inflammation of sebaceous glands or ducts may contribute to follicular damage.

research Impact of systemic hormonal imbalances on sebaceous gland disorders: An in-depth review integrating clinical, endocrine, and therapeutic insights

August 2026 in “Cosmoderma”

This review identifies sebaceous gland disorders as key indicators of hormonal imbalances, detailing how various hormones affect sebaceous function, and emphasizes a multidisciplinary approach to improve diagnosis and management by integrating endocrine, metabolic, and dermatologic insights.

research Sebaceous lipids are essential for water repulsion, protection against UVB-induced apoptosis, and ocular integrity in mice

32 citations , January 2016 in “Development”

This study introduced Scd3-Cre mice, which enabled sebocyte-specific manipulation, revealing that sebaceous lipid depletion impaired water repulsion, thermoregulation, and the ocular surface, resembling Meibomian gland dysfunction.

research Skin Barrier Dysfunction in Acne Vulgaris: Pathogenesis and Therapeutic Approaches

18 citations , October 2024 in “Medical Science Monitor”

This review discusses the mechanisms of skin barrier impairment in acne vulgaris and suggests strategies for its repair but reports no new clinical results.

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community No fearmongering /just facts on yesterday someone posting on eye issues

in Finasteride/Dutasteride 33 upvotes 1 year ago

Finasteride and dutasteride may not significantly impact meibomian gland function since these glands do not rely on DHT. Some users report dry eyes and other side effects from finasteride, but these may be influenced by other factors or medications.

community Does finasteride/dutasteride reverse aging?

in Chat 45 upvotes 1 year ago

Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community I was wrong about Dutastride. Let the I told you so comments rain in.

76 upvotes 10 months ago

Switching from dutasteride to finasteride caused increased hair loss, dandruff, depression, and erectile dysfunction. The user plans to return to dutasteride, possibly with minoxidil, and is considering dosing strategies to manage side effects and regrowth.

community You will lose hair if your prostaglandins aren't in balance

56 upvotes 1 year ago

Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

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