squalane
Research
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research Squalene-Containing Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Diphencyprone for Treating Alopecia Areata
This study found that nanostructured lipid carriers with more soybean phosphatidylcholine provided better skin retention and follicular targeting for diphencyprone compared to other formulations and controls.
research Quantification of Squalene and Lactic Acid in Hair Bulbs with Damaged Sheaths: Are They Metabolic Wastes in Alopecia?
In this study, researchers found that subjects with clinical alopecia had significantly higher levels of squalene in their hair bulbs compared to controls, suggesting squalene as a potential metabolic and pathogenic marker for certain alopecia conditions.
research Improvement of Hair Damage by Lipophilic Vitamin C (Ascorbyl Tetraisopalmitate)
This study found that applying a solution containing oil-soluble vitamin C to damaged hair improved hair cuticle condition and water repellency, suggesting a new cosmetic function beyond its known skin whitening effects.
research Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli
This article reviews the role of skin surface lipid in mediating environmental stressors and discusses potential therapeutic interventions, reporting no new experimental findings.
research TREM2 Macrophages Induced by Human Lipids Drive Inflammation in Acne Lesions
This study discovered that TREM2 macrophages influenced by squalene play a role in acne's development by hindering the killing of Cutibacterium acnes, helping explain why benzoyl peroxide is effective in treatment.
research Squarticles as a Lipid Nanocarrier for Delivering Diphencyprone and Minoxidil to Hair Follicles and Human Dermal Papilla Cells
This research reported that squarticles, nanoparticles made from sebum-derived lipids, enhanced the follicular delivery and skin accumulation of diphencyprone and minoxidil, indicating effective drug deposition with reduced systemic absorption in alopecia treatment.
research Characterization of the Lipid Composition at the Proximal Root Regions of Human Hair
This study observed that in Japanese females, hair lipid composition showed significant correlations, suggesting CH and CERs may act as a barrier against sebum-derived lipids.
research Prevention of Lipid Loss from Hair by Surface and Internal Modification
This study investigated lipid loss in hair caused by surfactants and found that surface and internal modifications can significantly protect different lipids from depletion, with internal modification preventing 52.0 to 81.3% of lipids in certain groups.
research On The Effects Of A Plant Extract Of Orthosiphon Stamineus On Sebum-Related Skin Imperfections
This study found that a cosmetic formula containing 2% Orthosiphon stamineus leaf extract significantly reduced skin oiliness and pore size, showing better results than a formula with 1% zinc gluconate.
research Hair Loss From Sebum
This research article discusses unsaturated compounds causing temporary hair loss in lab animals and reports no new results; previous studies indicated similar effects in humans.
research Sebaceous Gland Regeneration in Human Skin Xenografts
In this study, researchers observed that human sebaceous glands can regenerate in a mouse model using transplanted human skin, potentially offering a tool to study sebaceous gland biology and regeneration.
research Analysis of Lipids in the Medulla of Japanese Hair and Their Function
This study found that the medulla of Japanese hair contains unsaturated lipids such as squalene and oleic acid, which may contribute to hair glossiness.
research Free Internal Lipids in Hair From Pre- and Post-Menopausal Women
This study found that menopause alters hair lipids and reduces hair quality, with hormone replacement therapy mitigating some changes.
research Phytochemical Analysis of Eclipta Prostrata L. Leaves
This study identified various phytochemicals and compounds in Eclipta prostrata leaves using qualitative tests, FTIR, and GC-MS analysis, highlighting the presence of phytol and squalene among others.
research Refatting Rate of Human Hair Lipids After Exposure to Selenium Disulfide Detergents
This study found that both hard and soft selenium disulphide-based detergents significantly increased triglyceride levels in human hair, suggesting enhanced sebum production with reduced lipolytic activity, but showed no significant differences between their effects.
research Experimental and Theoretical Studies on the Interaction of Finasteride with Chitosan-Based Nanoniosomes
This study developed a new finasteride release system using chitosan-based nanoniosomes, observing that 70% of the drug was released over ten days in vitro, suggesting potential for prostate cancer prevention.
research Dual Case Reports for Lipid Loss from Human Hair
In this study, researchers identified two mechanisms of lipid loss from hair when exposed to surfactants, with the mechanism depending on the lipid's hydrophobicity.
research Backhousia Citriodora Leaf Extract: A New Active Solution to Control Hyper-Seborrhea for Multi-Ethnic Skins
This research observed that Backhousia citriodora leaf extract effectively reduced sebum production and improved sebum composition across different ethnicities, significantly decreasing skin oiliness and the likelihood of shiny skin when used in a cream applied twice daily for 28 days.
research Molecular Interactions of Natural and Synthetic Steroids in Female Hamsters’ Flank Organs
This study found that various steroids affected the mRNA expression of enzymes involved in lipid metabolism in hamster flank organs, with different impacts depending on the steroid and combination used.
research Phytochemical Profiling, Antibacterial, Antifungal, and Antioxidant Evaluation of Acrotrema Arnottianum Wight - An Ethnomedicinal Plant
This study suggests that Acrotrema arnottianum, a herb used in traditional medicine, contains biologically active metabolites like squalene and α-Tocopherol. It showed antibacterial effects against Staphylococcus aureus and antifungal properties against Candida albicans, while demonstrating antioxidant activity.