Nanotechnology in Dermatology

The document from 2014 reviews the use of nanotechnology in dermatology, emphasizing its potential in drug delivery systems, treatment of skin conditions, and cancer therapy. Nanoparticles, ranging from 1 nm to 100 nm, are used to enhance drug penetration through the skin and target specific conditions. A study by Friedman et al. from 2011 with a 23% response rate from 100 dermatology professionals in the USA indicated a lack of education on nanotechnology, highlighting the need for further research and safety evaluations. Nanotechnology applications in dermatology include improving bioavailability and efficacy of drugs like corticoids and retinoids, and using titanium dioxide and zinc oxide nanoparticles in sunscreens. For scalp diseases and alopecia, nanoparticles have shown to increase drug permanence in hair follicles, with treatments like minoxidil and finasteride showing improved efficacy when delivered through nanoparticles. Despite the promising applications, the document stresses the need for specific toxicological studies and safety standards for human use, as well as further understanding of the environmental and health impacts of nanoparticles.