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Glossary Drug Absorption

process by which a drug enters the bloodstream from administration

Drug absorption refers to the process by which a drug enters the bloodstream from its site of administration. This can occur through various routes such as oral, intravenous, or topical application. The efficiency and rate of absorption can be influenced by factors like the drug's formulation, the presence of food in the stomach, and the health of the gastrointestinal tract. Understanding drug absorption is crucial for determining the correct dosage and ensuring the drug's effectiveness.

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Research

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research Microneedles as Enhancer of Drug Absorption Through the Skin and Applications in Medicine and Cosmetology

55 citations , March 2018 in “Journal of pharmacy & pharmaceutical sciences”

This article reviews the applications of microneedle technology in drug delivery, dermatology, and cosmetics, but it presents no new experimental or clinical findings.

research Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs

8 citations , January 2021 in “Pharmaceutics”

This study found that using nanoporous silica entrapped lipid-drug complexes enhanced the solubility and bioavailability of dutasteride in beagle dogs.

research The role of tight junctions in skin barrier function and dermal absorption

156 citations , August 2016 in “Journal of controlled release”

This review summarizes current knowledge on tight junctions in mammalian skin and their role in drug delivery and interaction with other barrier components, but reports no new experimental results.

research Drug delivery to hair follicles

122 citations , March 2013 in “Expert opinion on drug delivery”

This review summarizes drug delivery strategies to hair follicles, highlighting physicochemical factors affecting penetration and the use of stimuli-responsive particulate carriers, but reports no new clinical findings.

research Cyclosporin A: a new drug in the field of canine dermatology

84 citations , March 2004 in “Veterinary Dermatology”

In randomized controlled trials, this research reports that cyclosporin is as effective as glucocorticoids for treating canine atopic dermatitis and has potential benefits for other immune-mediated skin conditions in dogs.

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Community Join

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community deeper understanding of microneedling

16 upvotes 3 years ago

Microneedling can enhance hair growth by increasing drug absorption and activating stem cells, with different needle depths serving distinct purposes. Users report success with microneedling, often in combination with treatments like minoxidil and finasteride, and emphasize waiting periods for topical application to avoid side effects.

community FIN/DUT with water, milk, coffee? What do you consume it with?

4 upvotes 5 years ago

People discuss taking finasteride and dutasteride with various drinks, noting that water is common, while some avoid grapefruit juice. Opinions vary on whether the choice of beverage affects drug absorption.

community Bloodwork on 0.5mg dutasteride

4 upvotes 1 week ago

The conversation discusses using 0.5mg dutasteride for hair loss and the decision to switch back to finasteride pills due to insufficient suppression. It highlights the importance of drug formulation and potential issues with absorption or degradation.

community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

5 upvotes 7 months ago

Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

community PP405 Drug in Action: Picture From Official Company Website

780 upvotes 1 year ago

PP405 shows promise for hair follicle reactivation with minimal side effects. Users recommend continuing Minoxidil and Finasteride until more results are confirmed.

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