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Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
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5 / 1000+ resultsresearch The Effect of St. John's Wort Treatment on Finasteride Pharmacokinetics and Identification of New Phase I and Phase II Metabolites in Humans
St. John’s wort changes how finasteride works in the body, possibly affecting its effectiveness.
research Michaelis-Menten Kinetic Modification: Space Pharmaceuticals Bioavailability Approaches Finasteride
Microgravity may increase drug bioavailability, potentially reaching up to 80%.
research Chapter 14: Principles of Drug Metabolism
Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.
research Saturable Binding of Finasteride to Steroid 5α-Reductase as Determinant of Nonlinear Pharmacokinetics
Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.
research The Biological Actions of Dehydroepiandrosterone Involve Multiple Receptors
DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
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community The story of RU58841/ PSK3841
by
Typical-Promise-3001
in Research
622 upvotes
1 year ago RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.
community How is it possible for someone to be a non responder to ORAL minoxidil?
Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.
community Serum DHT data wanted for insights into dutasteride efficacy. Please get in touch!
by
gnathan
in General
132 upvotes
1 year ago The conversation is about gathering serum DHT data from individuals taking dutasteride to investigate its efficacy, especially in cases with unexpectedly low DHT reduction. The aim is to explore potential genetic factors affecting drug metabolism.
community Why isn't anybody on topical bicalutamide?
Topical bicalutamide is discussed as a potential hair loss treatment. Other treatments mentioned include Minoxidil, finasteride, and RU58841.
community I'm thinking of incorporating tretinoin into my regimen after almost 4.5 years of being on min and 1 mg fin
The conversation is about incorporating tretinoin into a hair loss regimen after using minoxidil and finasteride for years, with discussions on the effectiveness of minoxidil and the potential benefits of adding tretinoin. Users also discuss the effectiveness of oral minoxidil and other topical treatments like diclofenac and fluocinolone.