TLDR Foams improve drug absorption and release in various medical applications.
The document reviewed the use of foam as a drug form, highlighting its advantages in drug delivery systems. Foams, being multiphase systems, were noted for their high surface area and low density, which enhanced drug absorption and solubility. Initially used for topical skin treatments, foams were well-received by patients and showed better absorption than ointments. The review discussed the potential of foams in oral medications, where they could increase drug solubility and modify release by holding drugs in their pores. Additionally, foams were used in parenteral applications, such as bone implants and antibiotic carriers, due to their ability to remain longer in the gastrointestinal tract and provide sustained drug release.
20 citations
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September 2015 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil foam promotes hair growth and reduces hair loss safely in men.
100 citations
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June 2011 in “Journal of The American Academy of Dermatology” 5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.
74 citations
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June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” Minoxidil foam enters hair follicles and skin for hair growth.
25 citations
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January 2010 in “International Journal of Pharmaceutics” Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.
2 citations
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May 2023 in “Nanomaterials” Microemulsions could improve skin drug delivery but face challenges like complex creation and potential toxicity.
27 citations
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August 2018 in “Therapeutic Delivery” Nanotechnology could make hair loss treatments more effective and reduce side effects, but more research is needed before it's available.
39 citations
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April 2011 in “Recent Patents on Drug Delivery & Formulation” Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.
September 2019 in “University of Huddersfield Repository (University of Huddersfield)” Nanoemulsions can effectively deliver antiseptic agents deep into the skin.
January 2025 in “Pharmaceuticals” Nanocarriers can improve antioxidant delivery to the skin but face safety and production challenges.