Effect of Minoxidil Topical Foam on Frontotemporal and Vertex Androgenetic Alopecia in Men: A 104-Week Open-Label Clinical Trial

September 2015 in “ Journal of The European Academy of Dermatology and Venereology ”

Varvara Kanti, K. Hillmann, Jan Kottner, Andrea Stroux, Donald E. Canfield, Ulrike Blume-Peytavi

minoxidil topical foam androgenetic alopecia hair growth hair loss frontotemporal vertex Rogaine

TLDR Minoxidil foam promotes hair growth and reduces hair loss safely in men.

This document summarizes five different studies that evaluated the effectiveness and safety of 5% minoxidil topical foam in treating androgenetic alopecia in men. The studies found that minoxidil topical foam was effective in promoting hair growth and reducing hair loss in both frontotemporal and vertex areas, while showing good safety and tolerability profiles with low rates of adverse effects. The studies suggest that minoxidil topical foam is a safe and effective treatment option for androgenetic alopecia in men.

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Research cited in this study

12 / 12 results

A Single-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Investigate the Efficacy and Safety of Minoxidil Topical Foam in Frontotemporal and Vertex Androgenetic Alopecia in Men

research A Single-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Investigate the Efficacy and Safety of Minoxidil Topical Foam in Frontotemporal and Vertex Androgenetic Alopecia in Men

19 citations , January 2015 in “Skin Pharmacology and Physiology”

Minoxidil foam effectively promotes hair growth and reduces hair loss in men.

Similar Response Patterns to Topical Minoxidil Foam 5% in Frontal and Vertex Scalp of Men with Androgenetic Alopecia: A Microarray Analysis

research Similar Response Patterns to Topical Minoxidil Foam 5% in Frontal and Vertex Scalp of Men with Androgenetic Alopecia: A Microarray Analysis

19 citations , September 2014 in “British Journal of Dermatology”

Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.

research Quality of Life Assessment in Male Patients with Androgenetic Alopecia: Results of a Prospective, Multicenter Study

101 citations , January 2012 in “Annals of Dermatology”

Men with hair loss experience lower quality of life, worsened by factors like age, severity, and treatment history.

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men

198 citations , October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft”

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

A Randomized, Single-Blind Trial of 5% Minoxidil Foam Once Daily Versus 2% Minoxidil Solution Twice Daily in the Treatment of Androgenetic Alopecia in Women

research A Randomized, Single-Blind Trial of 5% Minoxidil Foam Once Daily Versus 2% Minoxidil Solution Twice Daily in the Treatment of Androgenetic Alopecia in Women

100 citations , June 2011 in “Journal of The American Academy of Dermatology”

5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.

research S1 Guideline for Diagnostic Evaluation in Androgenetic Alopecia in Men, Women, and Adolescents

151 citations , August 2010 in “British Journal of Dermatology”

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men

research A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men

142 citations , August 2007 in “Journal of The American Academy of Dermatology”

New 5% minoxidil foam effectively promotes hair growth and is safe for use.

research An Open, Randomized, Comparative Study of Oral Finasteride and 5% Topical Minoxidil in Male Androgenetic Alopecia

71 citations , January 2004 in “Dermatology”

Oral finasteride works better than topical minoxidil for hair growth, both are safe.

A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

269 citations , August 2002 in “Journal of The American Academy of Dermatology”

5% minoxidil works better for hair growth and density, with minor irritation.

Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Application of 5% and 2% Topical Minoxidil, Placebo, or No Treatment

research Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Application of 5% and 2% Topical Minoxidil, Placebo, or No Treatment

115 citations , November 1999 in “Journal of The American Academy of Dermatology”

Minoxidil increases hair weight and count temporarily in men with hair loss.

research 2% Topical Minoxidil Solution in Male-Pattern Baldness: Preliminary European Results

26 citations , January 1987 in “Dermatology”

Topical minoxidil is safe and effective for some early male-pattern baldness cases.

research Topical Minoxidil for Androgenetic Alopecia: Optimizing the Chance for Success by Appropriate Patient Selection

11 citations , January 1987 in “Dermatology”

Minoxidil works for 56% of balding men with specific criteria.

Related Research

8 / 8 results

research A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss

1 citations , October 2022 in “PubMed”

Patients generally have positive attitudes towards using topical Minoxidil for hair loss treatment.

research Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil

1 citations , August 2022 in “JAAD case reports”

Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.

research Scalp Vascularization as a Marker of Topical Minoxidil Treatment Efficacy in Patients with Androgenetic Alopecia

March 2021 in “Postepy Dermatologii I Alergologii”

Minoxidil works equally well for hair growth regardless of scalp blood flow.

research Pustular Dermatosis of the Scalp Due to Topical Minoxidil 5%

3 citations , January 2018

A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.

research Scalp Psoriasiform Contact Dermatitis with Acute Telogen Effluvium Due to Topical Minoxidil Treatment

14 citations , January 2015 in “Skin appendage disorders”

Minoxidil treatment for hair loss can cause scalp allergy and severe hair loss.

research Disorders of Hair

July 2013 in “DeckerMed Medicine”

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research Treatments for Androgenetic Alopecia and Alopecia Areata

72 citations , January 2001 in “Drugs”

Minoxidil and finasteride treat hair loss; more research needed for other options.

research Topical Minoxidil in Androgenetic Alopecia: Scandinavian and Middle East Experience

11 citations , July 1988 in “International Journal of Dermatology”

The study found that using 2% minoxidil solution can help grow hair and is safe.