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    GlossaryFixed Drug Eruption

    recurrent skin reaction at the same site from specific drugs

    A Fixed Drug Eruption (FDE) is a type of allergic reaction to a medication that recurs in the same location on the skin each time the drug is taken. It typically presents as a well-defined, round or oval, red or purple patch that may blister and leave a dark mark after healing. Common culprits include antibiotics, pain relievers, and other medications.

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      Fixed-Drug Eruption Due to Dextromethorphan

      research Fixed-Drug Eruption Due to Dextromethorphan

      8 citations, July 1990 in “Archives of Dermatology”
      A woman had a skin reaction from a cough suppressant, dextromethorphan, which is a new cause of fixed-drug eruption.
      Drug Eruptions

      research Drug Eruptions

      November 2014
      Any medication can cause skin reactions, some due to allergies and others due to dosage or genetic factors.

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      community Binding affinity of pyrilutamide!

      in Update  167 upvotes 2 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community Earliest we can get legitimate pyrilutamide

      in Research/Science  47 upvotes 2 years ago
      Pyrilutamide, a drug in phase 3 trials in China, potentially becoming available in late 2023 or early 2024; Finasteride being used as a current treatment for hair loss; and the possibility of joining a group buy for black market versions of Pyrilutamide.

      community I talked to urologist about Finasteride and just wanted to share what he said

      in Finasteride  234 upvotes 7 years ago
      The effects of Finasteride, a drug used to treat hair loss, prostate problems and other conditions. The post by iaskedadoctor describes the conversations they had with a Urologist about the effects of the drug on DHT levels throughout the body, how lower doses are beneficial in reducing side effects, how erectile dysfunction can be psychological as well as physiological, how morning erections are not necessarily important, and how persistent side effects appear to be rare. People also shared their experiences with taking Finasteride for hair loss, including potential side effects such as reduced ejaculate force and development of man boobs.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 4 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.