Fullerene C60 with Cytoprotective and Cytotoxic Potential: Prospects as a Novel Treatment Agent in Dermatology
August 2016
in “
Experimental Dermatology
”
Fullerene C60 radical scavenger oxygen radical generator inflammatory diseases acne vulgaris alopecia photo-aging skin cancer microbial infections fullerene C60 derivatives physicochemical properties in vitro in vivo Fullerene antioxidant oxidative stress skin inflammation acne hair loss skin aging dermatological treatments skin infections fullerene derivatives lab studies animal studies
Studysummary This viewpoint essay discusses the potential of fullerene C60 derivatives as novel treatment agents in dermatology, highlighting their ability to act as both radical scavengers and oxygen radical generators.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Fullerene C60 exhibited both cytoprotective and cytotoxic properties, making it a potential novel treatment in dermatology. It acted as a radical scavenger and generated reactive oxygen species (ROS), which could reduce oxidative stress-related skin disorders like psoriasis, acne, and alopecia areata. Functionalized C60 showed less acute toxicity and no adverse skin reactions. It demonstrated protective effects against UV radiation, reduced acne inflammation, aided post-laser treatment care, promoted hair growth, and improved wound healing. Despite its use in cosmetics for anti-aging and skin hydration, the exact fate of C60 after skin application remained unclear, necessitating further research.
