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Glossary Inflammatory Diseases

conditions where immune system attacks body's own tissues

Inflammatory diseases are conditions where the body's immune system mistakenly attacks its own tissues, leading to inflammation. This can cause symptoms like redness, swelling, pain, and loss of function in the affected areas. Examples include rheumatoid arthritis, psoriasis, and inflammatory bowel disease. These diseases can affect various organs and systems, and managing them often requires a combination of medication, lifestyle changes, and sometimes surgery.

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Research

5 / 1000+ results

research The emerging role of Janus kinase inhibitors in the treatment of autoimmune and inflammatory diseases

70 citations , October 2020 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

This review discusses the JAK-STAT pathway and the use of FDA-approved JAK inhibitors for autoimmune and inflammatory diseases but reports no new research findings.

research Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases

6 citations , January 2023 in “International journal of molecular sciences”

This review discusses the bidirectional interactions between human mast cells and CD8 T cells in the skin, particularly in the context of disorders like psoriasis, atopic dermatitis, and vitiligo, and reports no new findings.

research Evidence of a Causal Relationship Between Body Mass Index and Immune-Mediated and Inflammatory Skin Diseases and Biomarkers: A Mendelian Randomization Study

2 citations , November 2024 in “Clinical Cosmetic and Investigational Dermatology”

This Mendelian randomization study suggests a causal link between higher BMI and increased risk of psoriasis, atopic dermatitis, and hidradenitis suppurativa, potentially due to elevated biomarkers such as triglycerides and C-reactive protein.

research Prevalence of autoimmune and inflammatory diseases and mental health conditions among an alopecia areata cohort from a US administrative claims database

1 citations , June 2023 in “Journal of Dermatology”

This study found that patients with alopecia areata had a higher prevalence of autoimmune, inflammatory, and mental health conditions compared to a matched cohort without alopecia areata.

research The follicular microbiome in hair-follicle-associated inflammatory diseases: A systematic review

June 2026 in “Clinical and Experimental Dermatology”

This study reviewed 55 studies to assess the bacterial microbiome in hair follicles across different inflammatory skin and hair conditions, reporting shifts in the abundance of Cutibacterium and Staphylococcus among various diseases, though the causal significance remains unclear.

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Community Join

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community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Any chances of my hairloss being inflammatory?

5 upvotes 2 weeks ago

A 20-year-old male has been experiencing hair loss since age 15-16 and is using oral minoxidil, dutasteride, and ketoconazole shampoo, with previous use of oral finasteride and topical minoxidil. He has stabilized hair loss but seeks to rule out inflammatory or immune-related causes, considering a scalp biopsy, and is supplementing with vitamin D3, B12, and iron.

community We Need A Solution For The Inflammatory Response related To AGA

in Research/Science 16 upvotes 2 years ago

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

community Has anyone here tried taking GLA supplements?

1 upvotes 1 year ago

GLA may help with hair loss due to its anti-inflammatory properties and 5ar enzyme inhibition. It's considered potentially more important than biotin, especially for those already using finasteride and dutasteride.

community Telogen Effluvium/Chronic TE and immune-related hair loss advice

5 upvotes 8 years ago

Chronic Telogen Effluvium can be managed by avoiding inflammatory foods, exercising, staying hydrated, and using supplements like krill oil, saw palmetto, or licorice root. Minoxidil is discouraged due to its cost and potential for worsening hair loss, while castor oil is recommended to strengthen hair roots and reduce shedding.

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Learn

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learn Cetirizine

What makes cetirizine a unique anti-inflammatory option for your scalp? Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is a few small trials in pattern hair loss (none in inflammatory scalp disease), so scalp use is off-label and experimental.

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn capsicum

Is capsicum safe for sensitive scalps or inflammatory hair loss? Capsicum may irritate sensitive scalps and worsen inflammatory hair loss.

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Clinics

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