Fullerene Nanoparticles in Dermatological and Cosmetic Applications
October 2016
in “
Nanomedicine: Nanotechnology, Biology and Medicine
”
fullerene nanoparticles antioxidant properties sunscreens skin whitening anti-aging creams acne treatment hair growth stimulation UV damage reactive oxygen species keratinocyte differentiation acne lesions hair growth skin penetration cellular uptake cytotoxicity fullerenes antioxidants sunscreen skin lightening anti-aging acne UV protection ROS keratinocytes acne reduction hair stimulation skin absorption cell uptake toxicity
Studysummary This review reports on the dual aspect of fullerene in skincare, highlighting its beneficial antioxidant properties as well as potential toxicity and skin cell reactions, while identifying areas for future research.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The document from April 1, 2017, reviews the use of fullerene nanoparticles in dermatology and cosmetics, emphasizing their antioxidant properties and potential in skin care products such as sunscreens, skin whitening, anti-aging creams, acne treatment, and hair growth stimulation. Fullerenes are shown to protect against UV damage, reduce reactive oxygen species, and promote keratinocyte differentiation. Clinical studies have demonstrated their effectiveness in reducing acne lesions and stimulating hair growth. Despite these benefits, concerns about fullerene toxicity and dermal reactions are noted, with the need for more research on their safety. The document also explores fullerene's skin penetration and cellular uptake, indicating that while there is no acute toxicity at lower doses, higher concentrations can be cytotoxic. The review concludes that fullerenes hold promise in dermatological applications but require further study to fully understand their toxicological profile and interactions with the skin.
