Fullerene Nanoparticles in Dermatological and Cosmetic Applications

The document from April 1, 2017, reviews the use of fullerene nanoparticles in dermatology and cosmetics, emphasizing their antioxidant properties and potential in skin care products such as sunscreens, skin whitening, anti-aging creams, acne treatment, and hair growth stimulation. Fullerenes are shown to protect against UV damage, reduce reactive oxygen species, and promote keratinocyte differentiation. Clinical studies have demonstrated their effectiveness in reducing acne lesions and stimulating hair growth. Despite these benefits, concerns about fullerene toxicity and dermal reactions are noted, with the need for more research on their safety. The document also explores fullerene's skin penetration and cellular uptake, indicating that while there is no acute toxicity at lower doses, higher concentrations can be cytotoxic. The review concludes that fullerenes hold promise in dermatological applications but require further study to fully understand their toxicological profile and interactions with the skin.