Female Pattern Hair Loss: A Clinical and Pathophysiological Review

    Paulo Müller Ramos, Hélio Amante Miot
    Image of study
    TLDR Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.
    This document is a clinical and pathophysiological review of Female Pattern Hair Loss (FPHL), which is the main cause of hair loss in adult women. FPHL is influenced by genetic, hormonal, and environmental factors, and its pathogenesis is not yet fully understood. The disease shows an inconsistent response to treatment, and its prevalence increases with age. FPHL strongly affects self-esteem and negatively impacts the patients' quality of life. The document includes information on the prevalence of FPHL in different populations, as well as its association with other conditions such as polycystic ovary syndrome and metabolic syndrome. The document also discusses the genetics and pathophysiology of FPHL, including the role of androgens and prostaglandins in hair growth. Overall, the document highlights the need for further research to improve the quality of life for patients affected by FPHL.
    Discuss this study in the Community →

    Research cited in this study

    93 / 93 results

    Related Community Posts Join

    6 / 1000+ results

      community For the ladies: Spironolactone for FPHL

      in Female  12 upvotes 7 years ago
      A 34 year old female with androgenic alopecia who has tried treatments such as Spironolactone, Desogen, Minoxidil and Finasteride in order to address her hair loss. It also details the experiences of other women taking Spironolactone for Female Pattern Hair Loss (FPHL).
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community One+ year 1mg Fin, Ketoconazole, and 3.75 Oral Min. I have DUPA. Switched from Topical to Oral Min.

      in Progress Pictures  142 upvotes 2 years ago
      A user's experience with hair loss treatments such as finasteride, ketoconazole, and oral minoxidil that have not yielded any results; other users suggest shaving the head or getting a wig, while others offer additional advice such as seeing a dermatologist, checking thyroid levels, switching to dutasteride and adding needling, and trying stemoxydine.

      community Finasteride 5mg for female pattern hair loss

      in Female  7 upvotes 4 years ago
      The user's experience of using Finasteride 5mg and Aldactone 50mg to treat Female Pattern Hair Loss, as well as their use of PRP injections for further hair growth.

      community Spironolactone Update

      in Female  11 upvotes 7 years ago
      A woman's experience with Spironolactone as treatment for female pattern hair loss, including the effects of increasing dosage and her doctor's recommendation to try finasteride if no results are seen after 6 months. Other users have also shared their experiences with using finasteride for this condition.

      community Got my DHT levels checked. 38 year old female. Still losing hair.

      in Female  10 upvotes 6 months ago
      A 38-year-old female is experiencing hair loss despite having almost undetectable DHT levels after using dutasteride. Suggestions include checking for PCOS, thyroid issues, adjusting diet, considering the impact of birth control, and trying treatments like tretinoin, redensyl, retinol, and minoxidil with derma stamping.

    Related Research

    9 / 9 results