Association of Androgenetic Alopecia With Mortality From Diabetes Mellitus and Heart Disease

May 2013 in “ JAMA Dermatology ”

Lin-Hui Su, Limei Chen, Sheng-Che Lin, Tony Hsiu Hsi Chen

androgenetic alopecia AGA diabetes mellitus heart disease male pattern baldness female pattern baldness diabetes cardiovascular disease

TLDR Hair loss links to higher death risk from diabetes and heart disease; not a direct cause, but a marker for risk factors.

This study found that moderate to severe androgenetic alopecia (AGA) is associated with a higher risk of mortality from diabetes mellitus and heart disease in both sexes. The study followed up with 7,126 participants for five years and suggests that AGA could be considered a marker for other underlying risk factors for diabetes mellitus and heart disease, but not a direct cause. AGA could be used to identify susceptible individuals who might benefit from interventions targeting multiple diabetes mellitus and heart disease risk factors.

View this study on archderm.jamanetwork.com →

Discuss this study in the Community →

Research cited in this study

11 / 11 results

research Androgenetic Alopecia and Cardiovascular Risk Factors in Men and Women: A Comparative Study

110 citations , July 2010 in “Journal of The American Academy of Dermatology”

Hair loss linked to higher heart disease risk in both men and women.

research Association of Androgenetic Alopecia with Metabolic Syndrome in Men: A Community-Based Survey

69 citations , April 2010 in “British Journal of Dermatology”

Balding men, especially young ones, may have higher risk of heart issues and diabetes; check cholesterol levels.

research Is Androgenetic Alopecia a Risk for Atherosclerosis?

38 citations , February 2009 in “Journal of The European Academy of Dermatology and Venereology”

Severe vertex pattern hair loss may indicate a higher risk for artery plaque buildup.

research Androgenetic Alopecia and Insulin Resistance in Young Men

50 citations , December 2008 in “Clinical Endocrinology”

Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.

research Evaluation of Lipid Levels in Androgenetic Alopecia Compared with Control Group

27 citations , March 2008 in “Journal of The European Academy of Dermatology and Venereology”

Men with a certain type of hair loss (AGA) have higher bad cholesterol and lower good cholesterol levels, making them more likely to get heart disease.

research Association of Androgenetic Alopecia and Hypertension

34 citations , August 2007 in “PubMed”

Balding in men is strongly linked to high blood pressure and family history.

research Baldness and coronary artery disease: the dermatologic point of view of a controversial issue.

50 citations , July 2001 in “PubMed”

Men who go bald before 30 may have a higher risk of heart disease.

research Early Onset of Androgenetic Alopecia Associated With Early Severe Coronary Heart Disease: A Population-Based, Case-Control Study

56 citations , June 2001 in “European journal of cardiovascular prevention & rehabilitation”

Early balding linked to higher heart disease risk.

research Early Androgenetic Alopecia as a Marker of Insulin Resistance

115 citations , September 2000 in “The Lancet”

Early hair loss may indicate risk of insulin resistance.

research The Risk of Coronary Heart Disease in Men with Androgenetic Alopecia

34 citations , March 1999 in “Journal of The European Academy of Dermatology and Venereology”

Bald men may have higher heart disease risk.

research Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex

666 citations , September 1977 in “British Journal of Dermatology”

Common baldness, also known as Androgenetic Alopecia, is caused by a combination of genetic factors and hormones called androgens.

Related Community Posts Join

6 / 1000+ results

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Sexual Dysfunction in Those with Androgenetic Alopecia on Dutasteride Versus Finasteride

in Finasteride/Dutasteride 113 upvotes 4 months ago

Dutasteride and finasteride have similar risks of sexual dysfunction for treating androgenetic alopecia. Users experience varying side effects, indicating individual differences in drug reactions.

community Been using Dutasteride, Ru58841, Minoxidil, and Ketaconozole for years. Still can't stop shed, recession or loss of density.

in Treatment 1 upvotes 1 year ago

Despite using dutasteride, RU58841, minoxidil, and ketoconazole for years, the user continues to experience severe hair loss and thinning. They seek advice after multiple dermatologists confirmed androgenetic alopecia (AGA) but offered no effective solutions.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 479 upvotes 1 year ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Being Safe on Oral Minoxidil: tl;dr on the literature.

in Research/Science 51 upvotes 10 months ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

Similar Research

5 / 1000+ results

research Comorbidities in Androgenetic Alopecia: A Comprehensive Review

September 2022 in “Dermatology and therapy”

Androgenetic alopecia is linked to heart disease, metabolic issues, and mental health problems.

Association Between Androgenetic Alopecia and Cardiovascular Risk Factors According to BASP Classification in Korean Androgenetic Alopecia

research Association Between Androgenetic Alopecia and Cardiovascular Risk Factors According to BASP Classification in Korean Androgenetic Alopecia

January 2016

Korean patients with androgenetic alopecia may have a higher risk of heart-related health issues and could benefit from early heart screening and healthier lifestyles.

Glycolipid and Hormonal Profiles in Young Men with Early-Onset Androgenetic Alopecia: A Meta-Analysis