Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing

December 2012 in “ Seminars in Cutaneous Medicine and Surgery ”

Pedram Yazdan

TLDR Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.

This document from 10 years ago discusses the genetics and pathogenesis of androgenetic alopecia, female pattern hair loss, and alopecia areata. Genetic factors play a significant role in these conditions, and molecular diagnostic testing could be useful for predicting hair loss development, diagnosing alopecia type, predicting disease severity, developing novel treatments, and determining response to therapy. The article also provides an overview of the pathophysiology of androgenetic alopecia and female pattern hair loss. The document mentions various genetic loci associated with these conditions and the potential for genetic testing to predict treatment response and develop personalized treatment plans.

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