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    Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing

    November 2012 in “ Seminars in Cutaneous Medicine and Surgery ”
    Pedram Yazdan
    Studysummary This review summarizes current understanding and genetic insights into androgenetic alopecia, female pattern hair loss, and alopecia areata, noting the potential future role of molecular diagnostics, but it reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 49

    1. Treatment Options for Alopecia: An Update, Looking to the Future Expert Opinion on Pharmacotherapy · 2012
    2. Susceptibility Variants on Chromosome 7p21.1 Suggest HDAC9 as a New Candidate Gene for Male-Pattern Baldness British Journal of Dermatology · 2011
    3. Association Analysis of Estrogen Receptor Beta Gene (ESR2) Polymorphisms with Female Pattern Hair Loss British Journal of Dermatology · 2011
    4. The Genetics of Alopecia Areata: What's New and How Will It Help Our Patients? Dermatologic therapy · 2011
    5. Histopathology of Alopecia Areata, Acute and Chronic: Why Is It Important to the Clinician? Dermatologic Therapy · 2011
    6. Alopecia Areata: Clinical Presentation, Diagnosis, and Unusual Cases Dermatologic Therapy · 2011
    7. Therapeutic Hotline: Genetic Variations in the Androgen Receptor Gene and Finasteride Response in Women with Androgenetic Alopecia Mediated by Epigenetics Dermatologic Therapy · 2011
    8. Physiological Changes in Scalp, Facial, and Body Hair After Menopause: A Cross-Sectional Population-Based Study of Subjective Changes British Journal of Dermatology · 2010
    9. Polymorphic CAG Repeat Numbers in the Androgen Receptor Gene of Female Pattern Hair Loss Patients Journal of Dermatology · 2010
    10. Evidence for Two Independent Functional Variants for Androgenetic Alopecia Around the Androgen Receptor Gene Experimental Dermatology · 2010
    11. Transcriptional Profiling in Alopecia Areata Defines Immune and Cell Cycle Control Related Genes Within Disease-Specific Signatures Genomics · 2010
    12. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    13. Peripheral Blood Gene Expression in Alopecia Areata Reveals Molecular Pathways Distinguishing Heritability, Disease, and Severity Genes and Immunity · 2010
    14. Alopecia Areata Update Journal of The American Academy of Dermatology · 2010
    15. Histopathology of Alopecia: A Clinicopathological Approach to Diagnosis Histopathology · 2009
    16. Evaluation of Androgen Receptor Gene as a Candidate Gene in Female Androgenetic Alopecia International Journal of Dermatology · 2009
    17. Gene-Wide Association Study Between the Aromatase Gene (CYP19A1) and Female Pattern Hair Loss British Journal of Dermatology · 2009
    18. Androgen Receptor Copy Number Variation and Androgenetic Alopecia: A Case-Control Study PLOS ONE · 2009
    19. Long-Term Treatment with Finasteride 1 mg Decreases the Likelihood of Developing Further Visible Hair Loss in Men with Androgenetic Alopecia PubMed · 2008
    20. Susceptibility Variants for Male-Pattern Baldness on Chromosome 20p11 Nature Genetics · 2008
    21. Male-Pattern Baldness Susceptibility Locus at 20p11 Nature Genetics · 2008
    22. Interventions for Alopecia Areata Cochrane library · 2008
    23. EDA2R Is Associated With Androgenetic Alopecia Journal of Investigative Dermatology · 2008
    24. Genome-Wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26 American Journal of Human Genetics · 2008
    25. Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007
    26. Lymphocytes, Neuropeptides, And Genes Involved In Alopecia Areata Journal of Clinical Investigation · 2007
    27. Alopecia in the United States: Outpatient Utilization and Common Prescribing Patterns Journal of the American Academy of Dermatology · 2007
    28. Baldness And The Androgen Receptor: The AR Polyglycine Repeat Polymorphism Does Not Confer Susceptibility To Androgenetic Alopecia Human Genetics · 2007
    29. Genomewide Scan for Linkage Reveals Evidence of Several Susceptibility Loci for Alopecia Areata The American Journal of Human Genetics · 2007
    30. The Hair Follicle as an Estrogen Target and Source Endocrine Reviews · 2006
    31. Clinical Approach to the Patient With Alopecia Seminars in Cutaneous Medicine and Surgery · 2006
    32. The Histopathology of Noncicatricial Alopecia Seminars in Cutaneous Medicine and Surgery · 2006
    33. Effectiveness of Finasteride on Patients with Male Pattern Baldness Who Have Different Androgen Receptor Gene Polymorphism Journal of Investigative Dermatology Symposium Proceedings · 2005
    34. Prevalence of Male and Female Pattern Hair Loss in Maryborough Journal of Investigative Dermatology Symposium Proceedings · 2005
    35. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005
    36. Genetic Basis of Male Pattern Baldness Journal of Investigative Dermatology · 2003
    37. The Expression of Insulin-Like Growth Factor 1 in Follicular Dermal Papillae Correlates with Therapeutic Efficacy of Finasteride in Androgenetic Alopecia Journal of The American Academy of Dermatology · 2003
    38. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    39. Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans Journal of Investigative Dermatology · 2002
    40. Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2001
    41. Polymorphism of the Androgen Receptor Gene Is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001
    42. The Genetics of Androgenetic Alopecia Clinics in Dermatology · 2001
    43. Hair Density, Hair Diameter, and the Prevalence of Female Pattern Hair Loss British Journal of Dermatology · 2001
    44. Diffuse Female Hair Loss: Are Androgens Necessary? British Journal of Dermatology · 1999
    45. Diagnosis: Alopecia Areata or Not? Seminars in Cutaneous Medicine and Surgery · 1999
    46. Prevalence of Male Pattern Hair Loss in 18–49 Year Old Men Dermatologic Surgery · 1998
    47. Androgen Receptor Polymorphisms (CAG Repeat Lengths) in Androgenetic Alopecia, Hirsutism, and Acne Journal of Cutaneous Medicine and Surgery · 1998
    48. Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes Journal of Investigative Dermatology · 1998
    49. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996

    Related research 11

    1. Utilizing Functional Genomics Approaches to Characterize Risk Genes in Alopecia Areata Columbia Academic Commons (Columbia University) · 2020
    2. Genetic and Molecular Aspects of Androgenetic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2018
    3. Identification of Functional Patterns of Androgenetic Alopecia Using Transcriptome Profiling in Distinct Locations of Hair Follicles Journal of Investigative Dermatology · 2017
    4. Genetics of Androgenetic Alopecia 2016
    5. Androgenetic Alopecia: Overview, Epidemiology, Pathophysiology, and Treatment Journal of the Egyptian Women's Dermatologic Society (Print) · 2013
    6. Inflammation in Androgenetic Alopecia and Hair Loss: Linking Neurosciences, Endocrinology, and Dermatology Hair transplant forum international · 2012
    7. Androgenetic Alopecia: Diagnosis and Treatment with a Focus on Recent Genetic Implications Journal of Drugs in Dermatology · 2009
    8. The Genetics of Hair Shaft Disorders Journal of The American Academy of Dermatology · 2008
    9. Advance in the Etiology Research of Androgenetic Alopecia Journal of Practical Dermatology · 2008
    10. The Genetics of Androgenetic Alopecia Clinics in Dermatology · 2001
    11. Serum Androgens and Genetic Linkage Analysis in Early Onset Androgenetic Alopecia Journal of Investigative Dermatology · 1999