Evidence for Two Independent Functional Variants for Androgenetic Alopecia Around the Androgen Receptor Gene

September 2010 in “ Experimental Dermatology ”

J Cobb, Sophie Zaloumis, Katrina J Scurrah, Stephen B. Harrap, Justine A. Ellis

androgen receptor AR male pattern baldness AGA androgenetic alopecia Chr20 region ChrX region

Studysummary In this study, researchers identified two independent genetic variants near the androgen receptor gene strongly associated with androgenetic alopecia in men.

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The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia

research The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia

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This study found that the AR-E211 A allele is associated with a lower risk of both metastatic prostate cancer and androgenetic alopecia in an Australian population.

research Polymorphism of the Androgen Receptor Gene Is Associated with Male Pattern Baldness

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This study found that specific genetic markers near the androgen receptor gene are significantly more common in men with male pattern baldness, suggesting a genetic component in its development.