Evaluation of Androgen Receptor Gene as a Candidate Gene in Female Androgenetic Alopecia
June 2009
in “
International Journal of Dermatology
”
![Image of study](/images/research/999ac1a2-a6f3-491c-84e6-a2fd299dfe50/medium/2881.jpg)
TLDR AR gene not major factor in female hair loss; different from male hair loss.
This study evaluated the androgen receptor (AR) gene as a candidate gene for female androgenetic alopecia (AGA) and found no significant difference in genotype or allele frequency between patients and controls. The study concluded that the AR gene is not a major contributing factor in the pathogenesis of female AGA and that female AGA should be considered a different disease from male AGA. The study suggests that other candidate genes affecting plasma and/or tissue androgen concentrations are required for phenotypic expression, and future genetic studies should be conducted on a larger scale with different types of female AGA.