Female Pattern Hair Loss: An Overview with Focus on the Genetics

June 2023 in “ Genes ”

Chao‐Chi Ho, Jeff Yi‐Fu Chen, Wen‐Li Hsu, Sebastian Yu, Wei-Chiao Chen, Szu‐Hao Chiu, Huiru Yang, Sheng-Yao Lin, Chieh‐Shan Wu

Female Pattern Hair Loss genetic factors inflammation nutrition hormonal factors topical treatments systemic treatments surgical interventions vitamin D nutritional supplements FPHL

Studysummary This review discusses the genetic differences between male and female pattern hair loss and highlights the uncertainty surrounding genetic factors in female pattern hair loss, but reports no clinical results.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The review "Female Pattern Hair Loss: An Overview with Focus on the Genetics" discusses the genetic factors contributing to Female Pattern Hair Loss (FPHL). It indicates that the genetic factors for Male Androgenetic Alopecia (M-AGA) do not account for FPHL, suggesting different genes are involved. The exact genetic cause of FPHL remains unclear. The review also discusses the role of inflammation, nutrition, and hormonal factors in FPHL, with a significant correlation found between maternal family history and early onset FPHL. The document also explores various treatment options for FPHL, including topical treatments, systemic treatments, surgical interventions, and the potential of vitamin D and other nutritional supplements. However, more research is needed to understand the genetic mechanisms of FPHL and to develop personalized treatment strategies.

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