Vitamin D
aka - calciferol
- cholecalciferol
🛒 Where to find Vitamin D
Tracking 2 topical products and 4 oral products by companies like Farmacia Tristaina / Andorra, Hims, Roman, jack health and oxfordon line pharmacy. View all 6 products »Vitamin D, known for its role in bone health and calcium metabolism, has also been implicated in skin health, including the regulation of hair growth. Historically, vitamin D was discovered in the early 20th century during investigations into rickets, a bone disorder in children caused by vitamin D deficiency. Since then, research has expanded into the vitamin's broader effects on human health, revealing its significance in immune function, cardiovascular health, and skin condition, among others.
In the realm of alopecia, vitamin D's mechanisms of action are complex and multifaceted. It interacts with the skin and hair follicles through the vitamin D receptor (VDR), which is present in various skin cells, including keratinocytes and hair follicle cells. Studies suggest that vitamin D plays a role in the normal cycling of hair follicles, promoting the transition from the resting phase (telogen) to the growth phase (anagen). Deficiency in vitamin D has been linked to various forms of hair loss, including alopecia areata (AA), a condition characterized by patchy hair loss, and possibly even androgenetic alopecia (AGA), the common form of hair thinning and balding.
Research on vitamin D as it relates to hair, hair growth, or loss has produced intriguing findings. For example, a review highlighted the importance of vitamin D in skin health, suggesting that deficiency might contribute to conditions like psoriasis, acne, and alopecia. Studies have shown that patients with AA often have lower levels of serum 25-hydroxyvitamin D, implying a potential link between vitamin D status and autoimmune hair loss. However, the relationship between vitamin D and hair growth is not straightforward, with research indicating that while vitamin D plays a critical role in hair follicle cycling, supplementation alone may not fully reverse hair loss conditions.
The sentiment within the community towards vitamin D and its impact on hair loss is that it's probably only relevant if you have a deficiency, but it has been suggested that most people in the northern hemisphere have a moderate deficiency. While some individuals report improvements in hair quality and density with vitamin D supplementation, especially in cases of identified deficiency, others remain skeptical of its efficacy as a standalone treatment for hair loss. Discussions often emphasize the importance of a comprehensive approach to hair loss treatment, which may include vitamin D supplementation among other therapies like finasteride and minoxidil. The community generally agrees on the value of testing for and addressing vitamin D deficiency, not only for potential benefits to hair health but also for overall well-being.
In summary, vitamin D is essential for various bodily functions, including the maintenance of healthy skin and potentially the regulation of hair growth. While its precise role in alopecia and hair loss is still under investigation, addressing vitamin D deficiency is a prudent step for individuals experiencing hair loss, as part of a broader treatment strategy.
Research
20 / 1000+ results
research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
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research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
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research Vitamin D Receptor: New Assignments for an Already Busy Receptor

research Deletion of DNA Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D
research Vitamin D: More Than a Bona Fide Hormone
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research Vitamin D Receptor: Molecular Signaling and Actions of Nutritional Ligands in Disease Prevention
research Evolution and Function of Vitamin D
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research Vitamin D Metabolism and Function in the Skin
research Lack of the Vitamin D Receptor Is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth
research Behavioral Characterization of Vitamin D Receptor Knockout Mice
research Genetic Disorders and Defects in Vitamin D Action
research Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis
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research Vitamin D and the Skin: Focus on a Complex Relationship
research Atrichia Caused by Mutations in the Vitamin D Receptor Gene Is a Phenocopy of Generalized Atrichia Caused by Mutations in the Hairless Gene
research Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands
research The Vitamin D Receptor Is a Wnt Effector That Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis
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