Assessment of Vitamin D Receptors in Alopecia Areata and Androgenetic Alopecia

May 2016 in “ Journal of Cosmetic Dermatology ”

Marwa M Fawzi, Sara H. Mahmoud, Shereen H. Ahmed, Olfat G. Shaker

vitamin D receptors alopecia areata androgenetic alopecia VDR serum VDR levels tissue VDR levels VDR mutations sex hormones topical vitamin D analogs vitamin D AA AGA

TLDR Low vitamin D receptor levels found in hair loss patients; topical vitamin D treatment suggested.

This study assessed the levels of vitamin D receptors (VDR) in patients with alopecia areata (AA) and androgenetic alopecia (AGA) compared to controls. The results showed significantly lower serum and tissue VDR levels in both AA and AGA patients compared to controls. The study suggests that VDR may play an important role in the pathogenesis of AA and AGA and recommends further studies on VDR mutations in AA and AGA, as well as the evaluation of a possible link between vitamin D, VDR, and sex hormones in the pathogenesis of AGA. The use of topical vitamin D analogs in the treatment of AA and AGA is also suggested.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community How a follicle next to it is so genetically different that it never miniaturized??

in Chat 219 upvotes 1 month ago

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community Why are there no studies on Topical Vitamin D3 for AGA?

in Research/Science 10 upvotes 1 year ago

Topical Vitamin D3 may stimulate hair growth and has been used for Alopecia Areata. There is a question about the lack of research on its use for Androgenetic Alopecia (AGA).

community The Real Cause Of Androgenetic Alopecia

in Research/Science 676 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community can someone please tell me its going to get better? im bawling my eyes out

in Female 67 upvotes 3 years ago

A 16-year-old girl is experiencing hair loss, which has worsened despite using minoxidil and multivitamins. Suggestions include broader hormone testing and considering other treatments like spironolactone if the hair loss is due to androgenic alopecia.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 1 year ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

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