Investigation of Variants of the Aromatase Gene (CYP19A1) in Female Pattern Hair Loss

    June 2011 in “ British Journal of Dermatology ”
    Silke Redler, M.P. Birch, Dmitriy Drichel, K. Dobson, Felix F. Brockschmidt, Rachid Tazi-Ahnini, Kathrin A. Giehl, Nadine Kluck, Rudolf Kruse, G. Lutz, Helmut H. Wolff, Thomas Becker, Markus M. Nöthen, Andrew G. Messenger, Robert E. Betz
    Image of study
    TLDR No link found between aromatase gene and female hair loss.
    The study investigated whether variants of the aromatase gene (CYP19A1) are associated with female pattern hair loss (FPHL). The results showed no significant association between any of the four variants and FPHL in the UK and German samples. The study suggests that CYP19A1 is not implicated in the pathophysiology of FPHL. The study concludes that the present results do not support the hypothesis that CYP19A1 directly influences susceptibility to FPHL.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results

    Related Community Posts Join

    6 / 312 results

      community We need to keep these snake oil companies accountable.

      in Treatment  120 upvotes 1 year ago
      Biotin is being misleadingly marketed as a primary treatment for androgenic alopecia, overshadowing more effective treatments like finasteride and minoxidil. There is a call for increased awareness and accountability to prevent misinformation.

      community Minoxidil is a 5ar inhibitor according to research

      in Research/Science  148 upvotes 5 months ago
      Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  33 upvotes 6 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  91 upvotes 3 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Why I deleted my YouTube channel Part I

      in Update  118 upvotes 4 years ago
      A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.

    Related Research

    4 / 4 results