Investigation of Variants of the Aromatase Gene (CYP19A1) in Female Pattern Hair Loss

    June 2011 in “ British Journal of Dermatology ”
    Silke Redler, M.P. Birch, Dmitriy Drichel, K. Dobson, Felix F. Brockschmidt, Rachid Tazi-Ahnini, Kathrin A. Giehl, Nadine Kluck, Rudolf Kruse, G. Lutz, Helmut H. Wolff, Thomas Becker, Markus M. Nöthen, Andrew G. Messenger, Robert E. Betz
    Image of study
    TLDR No link found between aromatase gene and female hair loss.
    The study investigated whether variants of the aromatase gene (CYP19A1) are associated with female pattern hair loss (FPHL). The results showed no significant association between any of the four variants and FPHL in the UK and German samples. The study suggests that CYP19A1 is not implicated in the pathophysiology of FPHL. The study concludes that the present results do not support the hypothesis that CYP19A1 directly influences susceptibility to FPHL.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results

    Related Community Posts Join

    6 / 267 results

      community We need to keep these snake oil companies accountable.

      in Treatment  120 upvotes 1 year ago
      Biotin is being misleadingly marketed as a primary treatment for androgenic alopecia, overshadowing more effective treatments like finasteride and minoxidil. There is a call for increased awareness and accountability to prevent misinformation.

      community Minoxidil is a 5ar inhibitor according to research

      in Research/Science  148 upvotes 1 month ago
      Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

      community Yes your lifestyle and diet has its role in hair loss.

      in Chat  296 upvotes 2 months ago
      Diet and lifestyle changes can reduce hair shedding but won't regrow hair lost to genetic male pattern baldness. Treatments like finasteride and dutasteride are necessary for significant hair regrowth.

      community Switch from fin to dut and its worse

      in Finasteride/Dutasteride  6 upvotes 5 months ago
      Switching from finasteride to dutasteride can worsen hair loss for some men due to increased testosterone levels. Topical treatments like RU58841 and Pyrilutamide are suggested to counteract these effects, but individual responses vary.

    Related Research

    4 / 4 results