TLDR 1 mg/day of low-dose oral minoxidil is effective and safe for treating female hair loss.
A 24-week randomized double-blind clinical trial evaluated the efficacy and safety of low-dose oral minoxidil (LDOM) at 0.25 mg/day versus 1 mg/day for treating female pattern hair loss (FPHL) in 30 women. The study found that the 1 mg/day dose significantly increased hair count (P < .001) compared to the 0.25 mg/day dose, which did not show significant improvement (P = .20). Both doses improved hair-shedding scores and quality of life, but no significant differences were observed between the groups in these measures. Mild facial hypertrichosis was noted in two patients on the 1 mg/day dose. The study concluded that LDOM 1 mg/day is effective and well-tolerated for FPHL, with superior efficacy to the 0.25 mg/day dose. Limitations included the small sample size and lack of a placebo group.
53 citations,
August 2019 in “Journal of The American Academy of Dermatology” Oral minoxidil and topical minoxidil 5% both effectively improve female-pattern hair loss with safe side effects.
8 citations,
August 2018 in “Anais Brasileiros De Dermatologia” Portuguese WAA-QoL questionnaire validated; FPHL severity, schooling, and phototypes affect patients' quality of life.
80 citations,
December 2017 in “International Journal of Dermatology” Low-dose oral minoxidil and spironolactone combo effectively reduces hair loss and improves hair density in women.
16 citations,
February 2017 in “Dermatology and Therapy” The new visual scale is a quick and effective way to measure hair loss in women.
January 2023 in “Journal der Deutschen Dermatologischen Gesellschaft” Early diagnosis and personalized treatment are crucial for managing hair loss in children.
1 citations,
October 2022 in “PubMed” Patients generally have positive attitudes towards using topical Minoxidil for hair loss treatment.
1 citations,
August 2022 in “JAAD case reports” Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.
3 citations,
January 2022 in “Journal of The American Academy of Dermatology” 1 mg/day of low-dose oral minoxidil is effective and safe for treating female hair loss.
1 citations,
October 2020 in “Journal of Cosmetic Dermatology” Using minoxidil and tofacitinib together can effectively treat severe hair loss.
April 2019 in “Zagazig university medical journal” 
14 citations,
January 2015 in “Skin appendage disorders” Minoxidil treatment for hair loss can cause scalp allergy and severe hair loss.
