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GlossaryGenotype

genetic composition influencing traits and characteristics

Genotype refers to the genetic makeup of an organism, specifically the set of genes it carries. It determines various traits and characteristics, such as eye color or susceptibility to certain diseases, by influencing how the organism's cells function and develop. For example, in the context of hair, a person's genotype can influence whether they are predisposed to conditions like alopecia.

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Single Nucleotide Polymorphisms Associated with Elevated Alanine Aminotransferase in Patients Receiving Asunaprevir Plus Daclatasvir Combination Therapy for Chronic Hepatitis C

research Single Nucleotide Polymorphisms Associated with Elevated Alanine Aminotransferase in Patients Receiving Asunaprevir Plus Daclatasvir Combination Therapy for Chronic Hepatitis C

2 citations, July 2019 in “PLOS ONE”

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

research Filaggrin Mutations as an Archetype for Understanding the Pathophysiology of Atopic Dermatitis

3 citations, August 2014 in “Journal of The American Academy of Dermatology”

Filaggrin mutations are linked to atopic dermatitis and help explain how genetics and environment affect the disease.

research Identification of the Ovine Keratin-Associated Protein 22-1 (KAP22-1) Gene and Its Effect on Wool Traits

42 citations, January 2017 in “Genes”

The gene KAP22-1 affects wool yield and fiber shape in sheep.

research Evaluation of Androgen Receptor Gene as a Candidate Gene in Female Androgenetic Alopecia

23 citations, May 2009 in “International Journal of Dermatology”

AR gene not major factor in female hair loss; different from male hair loss.

research Identification of the Ovine Keratin-Associated Protein 21-1 Gene and Its Association with Variation in Wool Traits

7 citations, July 2019 in “Animals”

The KRTAP21-1 gene affects wool yield and can help improve wool production.

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community Using 23andme to insight minoxidil response / SULT1A1 activity

in Minoxidil 11 upvotes 3 years ago

The conversation discusses using 23andme to determine if someone might respond well to minoxidil for hair loss treatment, and mentions the user's personal experience with micro-needling and minoxidil.

community Dutasteride: More Than a DHT Reducer – A Potential Androgen Receptor Inhibitor?

in Finasteride/Dutasteride 31 upvotes 2 months ago

Dutasteride may inhibit androgen receptors in addition to reducing DHT, potentially explaining its effectiveness over finasteride for hair loss. Concerns about its impact on muscle growth are debated, with some suggesting no significant effects.

community Why do so many people trash on finasteride?

in Chat 247 upvotes 3 weeks ago

Finasteride is effective for hair regrowth, especially on the crown, but can cause side effects like reduced libido and erectile dysfunction in some users. Opinions are mixed, with some reporting positive results without side effects and others experiencing significant issues.

community Follow up appointment with Donovan.

in Finasteride/Dutasteride 17 upvotes 1 year ago

The user was diagnosed with DUPA and initially treated with finasteride, then switched to dutasteride which worsened their hair loss. They are now returning to finasteride and adding treatments including oral minoxidil, Proscar, Viviscal, pumpkin seed oil, LLLT, and Nizoral shampoo, hoping for hair regrowth.

community Topical Finasteride reduced my DHT more than Oral Dutasteride

in Finasteride/Dutasteride 42 upvotes 2 years ago

Treatments for hair loss, including the experiences of topical finasteride and oral dutasteride. It also discusses Pyrilutamide, 0.025% topical concentration, Minoxidil, RU58841, and 1% finasteride gel dosage.