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    GlossaryAndrogen Receptor Gene (AR Gene)

    encodes a protein that binds male hormones like testosterone

    The Androgen Receptor Gene (AR Gene) is a gene located on the X chromosome that encodes the androgen receptor, a protein that binds to androgens, which are male hormones like testosterone. This receptor plays a crucial role in the development and maintenance of male characteristics, and mutations in the AR gene can lead to conditions such as androgen insensitivity syndrome and contribute to hair loss disorders like androgenetic alopecia.

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      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn GT20029

      research compound made to degrade androgen receptors in scalp

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      community Hair loss causes are still a myth.

      in Chat  16 upvotes 4 years ago
      The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

      community 3 months progress!! Fin + Min + Derma roller + Nizoral Shampoo.

      in Progress Pictures  565 upvotes 2 years ago
      The post discusses a user's successful hair regrowth after 3 months using 1 mg oral finasteride, oral minoxidil, weekly 1.5mm derma rolling, and Nizoral shampoo every other day, with no side effects. The conversation includes various responses, questions about the user's ethnicity and previous scalp condition, and suggestions for topical treatments.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 9 months ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.