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    GlossaryAndrogen Receptor mRNA

    carries genetic instructions to produce the androgen receptor protein

    Androgen Receptor mRNA (AR mRNA) is the messenger RNA that carries the genetic instructions from DNA to produce the androgen receptor protein. This protein binds to androgens, which are hormones like testosterone, and plays a crucial role in the development and maintenance of male characteristics, as well as in conditions like androgenetic alopecia (pattern hair loss).

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      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women

      learn GT20029

      research compound made to degrade androgen receptors in scalp

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      community Since there is so much hype for cosmeRNA and HMI-115...

      in Chat  48 upvotes 1 year ago
      Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

      community Anyone excited for CosmeRNA coming this month?

      in Product  171 upvotes 1 year ago
      CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

      community Physician here AMA – 30M oral Fin 1-1.25 mg daily

      in Update  47 upvotes 2 years ago
      Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

      community Why is dht bad for scalp hair but good for hair on the rest of body?

      in Satire  109 upvotes 1 year ago
      The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.