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    Glossary Androgen Receptor Gene

    encodes a protein that binds male hormones like testosterone

    The Androgen Receptor Gene (AR Gene) is a gene located on the X chromosome that encodes the androgen receptor, a protein that binds to androgens, which are male hormones like testosterone. This receptor plays a crucial role in the development and maintenance of male characteristics, and mutations in the AR gene can lead to conditions such as androgen insensitivity syndrome and contribute to hair loss disorders like androgenetic alopecia.

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    Research 10 of 1000+

    1. Clinical, Hormonal, Behavioral, and Genetic Characteristics of Androgen Insensitivity Syndrome in a Brazilian Cohort: Five Novel Mutations in the Androgen Receptor Gene The Journal of Clinical Endocrinology & Metabolism · 2003 · 174 citations
    2. Androgen receptor gene polymorphism and polycystic ovary syndrome 2012 · 45 citations
    3. Androgen receptor gene CAG repeat polymorphism in women with polycystic ovary syndrome Fertility and Sterility · 2008 · 44 citations
    4. Androgen receptor gene polymorphisms and risk for androgenetic alopecia: a meta-analysis Clinical and Experimental Dermatology · 2011 · 41 citations
    5. No Evidence that 2D:4D is Related to the Number of CAG Repeats in the Androgen Receptor Gene Frontiers in Endocrinology · 2013 · 40 citations
    6. Shorter CAG repeats in the androgen receptor gene may enhance hyperandrogenicity in polycystic ovary syndrome Gynecological Endocrinology · 2008 · 37 citations
    7. Androgen Receptor Gene Polymorphism and Prostate Zonal Volumes in Australian and Chinese Men Journal of Andrology · 2000 · 34 citations
    8. Androgen receptor gene CAG and GGN polymorphisms in infertile Nigerian men Journal of Endocrinological Investigation · 2009 · 26 citations
    9. Androgen receptor genetic variant predicts COVID‐19 disease severity: a prospective longitudinal study of hospitalized COVID‐19 male patients Journal of the European Academy of Dermatology and Venereology · 2020 · 26 citations
    10. Evidence of increased DNA methylation of the androgen receptor gene in occipital hair follicles from men with androgenetic alopecia British Journal of Dermatology · 2011 · 24 citations
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    Community 10 of 345

    1. If we lose hair because of our sensitivity to DHT, then why are we trying to reduce DHT when our sensitive androgen receptors are the culprit? Reddit · 6 Apr 2022
    2. Having androgen receptor density and sensitivity at wrong f*ing place Reddit · 17 Oct 2024
    3. Genetics are so weird and unpredictable Reddit · 13 Nov 2024
    4. Long term finasteride users; Did you notice any improvement after 2 years? Reddit · 11 Apr 2023
    5. Trying to understand finasteride side effects and post finasteride syndrome Reddit · 31 Oct 2020
    6. Fun thought experiment about halting hair loss permamently Reddit · 6 May 2024
    7. Chromosome 20’s balding effects and why fin likely isn’t working for some. Reddit · 10 Sept 2025
    8. Why do I have the feeling that this subreddit is flooded by Kintor employees? Reddit · 21 Aug 2024
    9. Tried addressing DHT and regrowth, wanting to try additional path Reddit · 20 Dec 2023
    10. Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others. Reddit · 18 May 2023
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    Learn 9 of 12

    1. Cyproterone a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
    2. Spironolactone Blood-pressure and diuretic drug with anti-androgen effects
    3. Neem Oil Oil from the neem tree, used in traditional remedies
    4. Clascoterone Topical androgen-receptor blocker, approved as an acne cream
    5. GT20029 Experimental topical drug designed to break down androgen receptors
    6. Pyrilutamide Experimental topical anti-androgen, also known as KX-826
    7. Bicalutamide Nonsteroidal anti-androgen, originally a prostate cancer drug
    8. RU58841 Experimental topical anti-androgen sold as a research chemical
    9. Fluridil Topical anti-androgen sold as a cosmetic lotion
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