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    Glossary Androgen Receptor Gene

    encodes a protein that binds male hormones like testosterone

    The Androgen Receptor Gene (AR Gene) is a gene located on the X chromosome that encodes the androgen receptor, a protein that binds to androgens, which are male hormones like testosterone. This receptor plays a crucial role in the development and maintenance of male characteristics, and mutations in the AR gene can lead to conditions such as androgen insensitivity syndrome and contribute to hair loss disorders like androgenetic alopecia.

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    1. Clinical, Hormonal, Behavioral, and Genetic Characteristics of Androgen Insensitivity Syndrome in a Brazilian Cohort: Five Novel Mutations in the Androgen Receptor Gene The Journal of Clinical Endocrinology & Metabolism · 2003 · 174 citations
    2. Androgen receptor gene polymorphism and polycystic ovary syndrome 2012 · 45 citations
    3. Androgen receptor gene CAG repeat polymorphism in women with polycystic ovary syndrome Fertility and Sterility · 2008 · 44 citations
    4. Androgen receptor gene polymorphisms and risk for androgenetic alopecia: a meta-analysis Clinical and Experimental Dermatology · 2011 · 41 citations
    5. No Evidence that 2D:4D is Related to the Number of CAG Repeats in the Androgen Receptor Gene Frontiers in Endocrinology · 2013 · 40 citations
    6. Shorter CAG repeats in the androgen receptor gene may enhance hyperandrogenicity in polycystic ovary syndrome Gynecological Endocrinology · 2008 · 37 citations
    7. Androgen Receptor Gene Polymorphism and Prostate Zonal Volumes in Australian and Chinese Men Journal of Andrology · 2000 · 34 citations
    8. Androgen receptor gene CAG and GGN polymorphisms in infertile Nigerian men Journal of Endocrinological Investigation · 2009 · 26 citations
    9. Androgen receptor genetic variant predicts COVID‐19 disease severity: a prospective longitudinal study of hospitalized COVID‐19 male patients Journal of the European Academy of Dermatology and Venereology · 2020 · 26 citations
    10. Evidence of increased DNA methylation of the androgen receptor gene in occipital hair follicles from men with androgenetic alopecia British Journal of Dermatology · 2011 · 24 citations
    11. THERAPEUTIC HOTLINE: Genetic variations in the androgen receptor gene and finasteride response in women with androgenetic alopecia mediated by epigenetics Dermatologic Therapy · 2011 · 16 citations
    12. Polymorphisms in androgen and estrogen receptor genes: effects on male aging Experimental Gerontology · 2004 · 12 citations
    13. Androgenetic alopecia and polymorphism of the androgen receptor gene (SNP rs6152) in patients with benign prostate hyperplasia or prostate cancer Journal of The European Academy of Dermatology and Venereology · 2014 · 11 citations
    14. Polymorphic CAG repeat numbers in the androgen receptor gene of female pattern hair loss patients Journal of Dermatology · 2010 · 10 citations
    15. Polymorphism of CAG and GGN repeats of androgen receptor gene in women with polycystic ovary syndrome Reproductive Biomedicine Online · 2015 · 9 citations
    16. The androgen receptor gene polyglycine repeat polymorphism is associated with memory performance in healthy Chinese individuals Psychoneuroendocrinology · 2009 · 9 citations
    17. CAG polymorphism in the androgen receptor gene in women may be associated with nodulocystic acne Postepy Dermatologii I Alergologii · 2019 · 7 citations
    18. Interaction between estrogens and androgen receptor genes microsatellites, prostate-specific antigen and androgen receptor expressions in breast cancer Neoplasma · 2010 · 6 citations
    19. Polymorphic CAG Repeat Numbers in the Androgen Receptor Gene of Female Pattern Hair Loss in a Han Chinese Population Dermatology · 2016 · 5 citations
    20. Lack of concordance and linkage disequilibrium among brothers for androgenetic alopecia and CAG/GGC haplotypes of the androgen receptor gene in Mexican families Journal of Cosmetic Dermatology · 2015 · 2 citations
    21. The effect of GGC and CAG repeat polymorphisms on the androgen receptor gene in response to finasteride therapy in men with androgenetic alopecia Journal of Research in Medical Sciences · 2019 · 1 citations
    22. The Association of Gene Expression and Single Nucleotide Polymorphism (rs 6152 SNP) in Androgen Receptor Gene with Recurrent Spontaneous Abortion (RSA) in Iraqi Women Medico-Legal Update · 2021
    23. Role of polymorphism of the androgen receptor gene and non-random X chromosome inactivation in the genesis of androgenic alopecia in women of childbearing potential Vestnik dermatologii i venerologii · 2011
    24. Role of polymorphism of the androgen receptor gene andnon-random x chromosome inactivation in the pathogenesisof androgenic alopecia Vestnik dermatologii i venerologii · 2010
    25. Androgen receptor gene polymorphism and biological age markers in men Scientific Reports · 2025
    26. Supplementary Material for: Polymorphic CAG Repeat Numbers in the Androgen Receptor Gene of Female Pattern Hair Loss in a Han Chinese Population 2016
    27. Evaluation of androgen receptor gene as a candidate gene in female androgenetic alopecia International Journal of Dermatology · 2009
    28. A genetic test for androgenetic alopecia: polymorphisms in the androgen receptor gene provide a genetic screening test for androgenetic alopecia and earlier medical intervention Hair transplant forum international · 2008
    29. Study on genetic polymorphisms of androgen receptor gene and 5α-reductase genes of Han men with androgenetic alopecia in the Eastern China Chinese Journal of Dermatology · 2006
    30. 409 ANDROGEN RECEPTOR GENE POLYMORPHISM (SNP RS6152) – ITS RELATIONSHIP TO ANDROGEN-SENSITIVE GENES EXPRESSION IN BENIGN PROSTATIC HYPERPLASIA, CARCINOMA OF THE PROSTATE AND ANDROGENETIC ALOPECIA European Urology Supplements · 2011