A Genetic Test for Androgenetic Alopecia: Polymorphisms in the Androgen Receptor Gene Provide a Genetic Screening Test for Androgenetic Alopecia and Earlier Medical Intervention

May 2008 in “ Hair transplant forum international ”

Sharon Keene

androgenetic alopecia male pattern baldness androgen receptor gene genetic variations cheek swab sensitivity early medical intervention AGA AR gene

TLDR A genetic test can identify people at risk of male pattern baldness early, allowing for quicker treatment.

This document presents a genetic test for androgenetic alopecia (AGA), or male pattern baldness. The test focuses on specific genetic variations in the androgen receptor (AR) gene that are associated with a higher or lower risk of developing AGA. The test is noninvasive and can be done using a cheek swab. It has been shown to have a high sensitivity for identifying individuals at higher risk for AGA, allowing for earlier medical intervention. However, confirmation tests may be needed to determine the need for treatment. Overall, the test provides a way to intervene early in AGA and can help patients seek appropriate treatment options.

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Research cited in this study

3 / 3 results

research Men With Kennedy Disease Have a Reduced Risk of Androgenetic Alopecia

41 citations, August 2007 in “British Journal of Dermatology”

Men with Kennedy disease have less chance of hair loss.

research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia

195 citations, July 2005 in “American Journal of Human Genetics”

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia

research The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia

76 citations, April 2005 in “Cancer Epidemiology, Biomarkers & Prevention”

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

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