Role of Polymorphism of the Androgen Receptor Gene and Non-Random X Chromosome Inactivation in the Pathogenesis of Androgenic Alopecia

    December 2010 in “ Vestnik dermatologii i venerologii
    A. N. Mareeva
    Image of study
    TLDR Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.
    The study conducted 12 years ago explored the connection between the polymorphism of the androgen receptor gene and non-random X chromosome inactivation in the onset of androgenic alopecia. The researchers discovered a link between the polymorphism of the androgen receptor gene, particularly the CAG repeat length in exon 1, and androgen-dependent diseases such as alopecia. This indicates that genetic factors and X chromosome inactivation patterns could have a substantial role in the development of androgenic alopecia.
    Discuss this study in the Community →

    Research cited in this study

    18 / 18 results

    Related Community Posts Join

    6 / 1000+ results

      community Maintaining hair until Breezula without Fin

      in Treatment  6 upvotes 5 years ago
      A 21-year-old male experienced side effects from topical finasteride and is seeking alternative treatments to maintain hair until Breezula is available. He is considering using minoxidil, Nizoral, micro-needling, and vitamin D supplementation, and may try CB or RU58841 if necessary.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  40 upvotes 5 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Hair loss causes are still a myth.

      in Chat  17 upvotes 3 years ago
      The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

      community Justin Trudeau really is one lucky guy

      in Satire  233 upvotes 1 week ago
      Justin Trudeau's full head of hair at 53 is humorously attributed to unpredictable genetics and possible use of finasteride. The conversation jokes about a resemblance to Fidel Castro, suggesting genetic luck or treatment use.

    Similar Research

    5 / 1000+ results