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    Glossary Androgen Receptor Gene

    encodes a protein that binds male hormones like testosterone

    The Androgen Receptor Gene (AR Gene) is a gene located on the X chromosome that encodes the androgen receptor, a protein that binds to androgens, which are male hormones like testosterone. This receptor plays a crucial role in the development and maintenance of male characteristics, and mutations in the AR gene can lead to conditions such as androgen insensitivity syndrome and contribute to hair loss disorders like androgenetic alopecia.

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    1. Cyproterone a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
    2. Spironolactone Blood-pressure and diuretic drug with anti-androgen effects
    3. Neem Oil Oil from the neem tree, used in traditional remedies
    4. Clascoterone Topical androgen-receptor blocker, approved as an acne cream
    5. GT20029 Experimental topical drug designed to break down androgen receptors