Genetic Variants in AR and SHBG and Resistance to Hormonal Castration in Prostate Cancer

    February 2013 in “ Medical Oncology ”
    Cátia Monteiro, Marta Velho Sousa, Ricardo Ribeiro … Rui Medeiros
    Studysummary In this study, researchers reported that the SHBG +5790 G>A polymorphism was associated with an increased risk of developing resistance to hormonal castration in advanced prostate cancer patients.
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    Research cited in this study 2

    1. Androgen Receptor Gene Polymorphisms and Risk for Androgenetic Alopecia: A Meta-Analysis Clinical and Experimental Dermatology · 2011
    2. Redefining Hormone Resistance in Prostate Cancer Therapeutic Advances in Medical Oncology · 2009