Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris

    August 2022 in “ IntechOpen eBooks
    María Librada Porriño‐Bustamante, María Antonia Fernández‐Pugnaire
    Image of study
    TLDR The best treatment for Frontal Fibrosing Alopecia and Lichen Planopilaris combines oral and topical medications to reduce symptoms and stop hair loss.
    The document discusses the treatment of Frontal Fibrosing Alopecia (FFA) and Lichen Planopilaris (LPP). The goal of treatment is to alleviate symptoms and halt hair loss progression, as hair regrowth is not possible once hair follicle destruction has occurred. Topical corticosteroids and tacrolimus can reduce inflammation but do not clearly slow alopecia. Intralesional corticosteroids may stimulate hair regrowth in some patients, especially for eyebrow alopecia in FFA. Systemic treatments, such as 5-alpha reductase inhibitors, are most effective in stabilizing FFA and promoting hairline regrowth. Hydroxychloroquine and oral immunomodulators are beneficial as oral treatments in LPP. Low-dose oral isotretinoin is the preferred treatment for facial papules in FFA. The combination of oral and topical treatments is the best therapeutic choice.
    Discuss this study in the Community →

    Research cited in this study

    50 / 50 results

    Related Community Posts Join

    6 / 393 results

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 9 months ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community 9 months on Fin - no progress , should I get on Dutasteride?

      in Chat  10 upvotes 1 month ago
      The user has been using finasteride, minoxidil, and nizoral for hair loss but hasn't seen regrowth, only maintenance. They are considering switching to dutasteride, which is believed to be more effective, but are concerned about potential side effects.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community I tried salt water to stop the DHT itch

      in Treatment  60 upvotes 2 years ago
      Treating the itch associated with male pattern baldness, which is believed to be caused by DHT. Potential treatments discussed include salt water, finasteride, ketoconazole, and RU58841.

      community How essential is scalp biopsy when dealing with hair loss?

      in Treatment  6 upvotes 1 month ago
      The user experienced hair loss despite using Fin and Min for 12 years and switched to Dutasteride, RU58841, and Keto scalp serum, but shedding and itch persist. They are considering increasing Dutasteride to 2.5mg and questioning the necessity of a scalp biopsy, with mixed opinions on its usefulness.

    Related Research

    8 / 8 results