Oral Isotretinoin Combined with Topical Clobetasol 0.05% and Tacrolimus 0.1% for the Treatment of Frontal Fibrosing Alopecia: A Randomized Controlled Trial

    April 2020 in “ Journal of Dermatological Treatment ”
    Hamidreza Mahmoudi, Anahita Rostami, Soheil Tavakolpour … Maryam Daneshpazhooh
    Studysummary This study found that combining oral isotretinoin with topical treatments was more effective than topical treatments alone for improving frontal fibrosing alopecia symptoms, despite some side effects.
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    Research cited in this study 18

    1. Frontal Fibrosing Alopecia: An Update on the Hypothesis of Pathogenesis and Treatment International Journal of Women's Dermatology · 2019
    2. Lichen Planopilaris: Retrospective Study on the Characteristics and Treatment of 291 Patients Journal of dermatological treatment · 2018
    3. Algorithmic Approach to the Treatment of Frontal Fibrosing Alopecia: A Systematic Review Journal of The American Academy of Dermatology · 2018
    4. Frontal Fibrosing Alopecia Presenting with Rapidly Spreading Facial Papules in a Premenopausal Woman: Case Report and Review Journal of the American Academy of Dermatology · 2018
    5. A Retrospective Analysis of Efficacy and Safety of Intralesional Triamcinolone Injections in the Treatment of Frontal Fibrosing Alopecia as Monotherapy or Concomitant Therapy International Journal of Trichology · 2018
    6. The Increasing Incidence of Frontal Fibrosing Alopecia: In Search of Triggering Factors Journal of the European Academy of Dermatology and Venereology · 2017
    7. Yellow Facial Papules Associated With Frontal Fibrosing Alopecia: A Distinct Histologic Pattern and Response to Isotretinoin Journal of the American Academy of Dermatology · 2017
    8. Efficacy of Oral Retinoids in Treatment-Resistant Lichen Planopilaris Journal of the American Academy of Dermatology · 2014
    9. Frontal Fibrosing Alopecia: A Retrospective Clinical Review of 62 Patients with Treatment Outcome and Long-Term Follow-Up International Journal of Dermatology · 2014
    10. Frontal Fibrosing Alopecia: A Multicenter Review of 355 Patients Journal of The American Academy of Dermatology · 2014
    11. Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris Journal of the European Academy of Dermatology and Venereology · 2014
    12. Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: A Systematic Review Journal of the European Academy of Dermatology and Venereology · 2013
    13. Frontal Fibrosing Alopecia: A Review of 60 Cases Journal of The American Academy of Dermatology · 2012
    14. Frontal Fibrosing Alopecia: A Clinical Review of 36 Patients British journal of dermatology/British journal of dermatology, Supplement · 2010
    15. Lichen Planopilaris: Retrospective Study and Stepwise Therapeutic Approach Archives of dermatology · 2009
    16. Frontal Fibrosing Alopecia: Treatment with Oral Dutasteride and Topical Pimecrolimus Journal of The European Academy of Dermatology and Venereology · 2008
    17. Lichen Planopilaris: Chronic Scarring Alopecia with Autoimmune Component Dermatologic therapy · 2008
    18. Primary Cicatricial Alopecias: Clinicopathology of 112 Cases Journal of the American Academy of Dermatology · 2003