Frontal Fibrosing Alopecia: A Retrospective Clinical Review of 62 Patients with Treatment Outcome and Long-Term Follow-Up

    April 2014 in “ International Journal of Dermatology ”
    Nusrat Banka, Thamer Mubki, M. J. Kristine Bunagan, Kevin J. McElwee, Jerry Shapiro
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    TLDR The treatment helped reduce symptoms and stabilize the hairline in most patients with Frontal Fibrosing Alopecia, but hair regrowth was limited.
    The retrospective clinical review studied 62 patients with Frontal Fibrosing Alopecia (FFA), predominantly postmenopausal Caucasian females, with symptoms like itching, pain, or burning reported by 65% of them. The treatment with intralesional corticosteroids, mainly intralesional triamcinolone acetonide, was effective in reducing symptoms and stabilizing the hairline in 97% of those treated, with 31% achieving remission for six months to six years. However, no patients saw regrowth in the frontal hairline, and only some had partial eyebrow regrowth. The study highlighted the association of FFA with autoimmune diseases in 14% of patients and emphasized the need for further research to establish effective treatment guidelines.
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