TLDR Oral isotretinoin effectively treats yellow facial papules in frontal fibrosing alopecia patients.
The document discussed frontal fibrosing alopecia (FFA), a condition characterized by progressive hairline recession, and its association with yellow facial papules. Histopathologic features of these papules included perifollicular inflammation, changes in elastic fibers, and sebaceous gland involvement. A proof-of-concept study demonstrated that oral isotretinoin effectively treated these facial papules in FFA patients. This finding was significant as it expanded the understanding of FFA's clinical manifestations and provided a potential therapeutic option.
Cited in this study
2 / 2 results
68 citations
,
October 2016 in “Experimental dermatology” FFA's causes may include environmental triggers and genetic factors.
339 citations
,
April 2014 in “Journal of The American Academy of Dermatology” Most patients with frontal fibrosing alopecia are postmenopausal women, and treatments like finasteride and dutasteride can improve or stabilize the condition.
7 citations
,
September 2021 in “Journal of the European Academy of Dermatology and Venereology” Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.
7 citations
,
May 2020 Low-dose oral isotretinoin improved hair loss and facial bumps in patients with a specific type of hair loss.
7 citations
,
February 2019 in “The American Journal of Dermatopathology” Researchers found a new early sign of Frontal Fibrosing Alopecia that could help avoid misdiagnosis.
1 citations
,
January 2019 in “Elsevier eBooks” FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.
21 citations
,
May 1996 in “Current problems in dermatology” Detailed patient history and physical exams are crucial for diagnosing hair loss.
5 citations
,
October 1988 in “Clinics in Dermatology” Minoxidil promotes hair growth but exact mechanism is unknown.
