Evaluating the Combined Efficacy of Oral Isotretinoin and Topical Tacrolimus Versus Oral Finasteride and Topical Tacrolimus in Frontal Fibrosing Alopecia: A Randomized Controlled Trial

    July 2022 in “ Journal of Cosmetic Dermatology ”
    Ghasem Rahmatpour Rokni, Seyed Naser Emadi, Abbas Dabbaghzade … Mohamad Goldust
    Studysummary This study found that in patients with frontal fibrosing alopecia, combining topical tacrolimus with isotretinoin is more effective after four weeks of treatment compared to tacrolimus with finasteride, though both regimens offered some benefit.
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    Research cited in this study 12

    1. Medical Therapy for Frontal Fibrosing Alopecia: A Review and Clinical Approach Journal of The American Academy of Dermatology · 2019
    2. Yellow Facial Papules Associated With Frontal Fibrosing Alopecia: A Distinct Histologic Pattern and Response to Isotretinoin Journal of the American Academy of Dermatology · 2017
    3. Case Series of Familial Frontal Fibrosing Alopecia and a Review of the Literature Journal of Cosmetic Dermatology · 2015
    4. Frontal Fibrosing Alopecia: A Multicenter Review of 355 Patients Journal of The American Academy of Dermatology · 2014
    5. Frontal Fibrosing Alopecia: A Review of 60 Cases Journal of The American Academy of Dermatology · 2012
    6. Successful Treatment of Melasma Using a Combination of Microdermabrasion and Q-Switched Nd:YAG Lasers Lasers in surgery and medicine · 2012
    7. Frontal Fibrosing Alopecia: A Clinical Review of 36 Patients British journal of dermatology/British journal of dermatology, Supplement · 2010
    8. Frontal Fibrosing Alopecia: Clinical Presentations and Prognosis British journal of dermatology/British journal of dermatology, Supplement · 2008
    9. Frontal Fibrosing Alopecia: Treatment with Oral Dutasteride and Topical Pimecrolimus Journal of The European Academy of Dermatology and Venereology · 2008
    10. Frontal Fibrosing Alopecia: Diagnostic and Therapeutic Assessment Actas Dermo-Sifiliográficas · 2007
    11. Frontal Fibrosing Alopecia in Postmenopausal Women Journal of The American Academy of Dermatology · 2004
    12. Clinical Pharmacokinetics and Pharmacodynamics of Finasteride Clinical Pharmacokinectics · 1996