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research Topical Tacrolimus in the Treatment of Erosive Pustular Dermatosis of the Scalp

23 citations , November 2007 in “Journal of cutaneous medicine and surgery”

This case report suggests that topical tacrolimus may effectively manage erosive pustular dermatosis of the scalp and reverse skin atrophy, although long-term use requires monitoring for side effects.

research Erosive pustular dermatosis and associated alopecia successfully treated with topical tacrolimus

22 citations , August 2011 in “Journal of the American Academy of Dermatology”

This article highlights that erosive pustular dermatosis of the scalp is often under-diagnosed in the United States, potentially leading to unnecessary surgery.

research FOCAL HYPERTRICHOSIS DURING TOPICAL TACROLIMUS THERAPY FOR CHILDHOOD VITILIGO

21 citations , January 2005 in “Pediatric Dermatology”

An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.

research Topical Tacrolimus (FK506): Treatment Failure in Four Cases of Alopecia Universalis

19 citations , September 2002 in “Acta dermato-venereologica”

In this retrospective study, anti-tuberculous agents, likely rifampicin, were effective adjunctive therapies for a chalazion, coinciding with spontaneous drainage in a patient with rosacea.

research Erosive pustular dermatosis of the scalp successfully treated with oral prednisone and topical tacrolimus

16 citations , October 2013 in “Anais Brasileiros de Dermatologia”

In this case report, an elderly woman with erosive pustular dermatosis of the scalp showed complete closure of eroded areas after treatment with prednisone and topical tacrolimus, resulting in stable scarring alopecia.

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community Topical Tacrolimus For Androgenetic Alopecia (AGA)

6 upvotes 2 weeks ago

Topical tacrolimus is being considered for androgenetic alopecia, though its effectiveness is unproven. Other treatments mentioned include minoxidil, dutasteride, cyclosporine, and teicoplanin, with discussions on blocking the prolactin receptor for hair growth.

community Help! Minoxidil or Duta to avoid Shed of long hair.

7 upvotes 2 years ago

The user is considering using Tacrolimus Solution and topical Dutasteride to avoid shedding caused by Minoxidil, which they fear may lead to facial side effects. They are also concerned about scalp sensitivity and are exploring different treatment bases to manage seborrheic dermatitis.

community I always hear the advice to reduce scalp inflammation. What are some non-steroidal ways to reduce inflammation?

in Treatment 13 upvotes 1 year ago

Non-steroidal ways to reduce scalp inflammation include using topical melatonin, urea shampoo, Zyrtec, turmeric with black pepper, omega-3 supplements, a self-made topical solution with cetirizine, melatonin, and piroctone olamine, ketoconazole shampoo, witch hazel shampoo, tacrolimus, and lifestyle changes like a healthy diet and regular exercise. Some users also mentioned unconventional methods like infrared light therapy and a carnivore diet.

community I had claude create a protocol only using fda approved drugs.

4 upvotes 8 months ago

A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

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Learn

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learn Cetirizine

Is topical cetirizine effective for androgenetic alopecia in women? Topical cetirizine is not an approved product and its use for female-pattern hair loss is off-label. The evidence is one small pilot study in mixed-sex patients and one randomized trial in 66 women where cetirizine was added to minoxidil; it is unproven on its own.

learn Valproic acid

How is valproic acid being explored differently in topical hair products compared to its traditional oral medical use? Topical valproic acid is being studied for local effects on the hair follicle rather than the whole-body effects of the oral drug. The human evidence is one small randomized 24-week trial of an 8.3% spray; no topical valproate product is approved for hair loss.

learn Bicalutamide

Is topical bicalutamide a safer alternative to finasteride? There is no published human trial of topical bicalutamide for hair loss, and no licensed topical product exists, so it cannot be called safer than finasteride — or shown to work at all. Oral finasteride has decades of trial data with a documented side-effect profile, and topical finasteride has a phase III trial behind it.

learn Rapamycin

Does topical rapamycin actually help reactivate dormant hair follicles? No study in living people has shown that topical rapamycin reactivates hair follicles; the evidence is from mice and cultured follicles.

learn Vitamin D

Are topical Vitamin D treatments useful for alopecia? Small, short trials suggest topical vitamin D analogues such as calcipotriol may help some people with mild patchy alopecia areata. There is no trial evidence that they help pattern hair loss.

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